The treatment of mammary tumours in the bitch and a comparison with the cat

Wilkinson, GT

doi:10.1136/vr.89.1.13

Cited by 8 publications

(9 citation statements)

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“…En bloc mastectomy of the affected gland(s), ipsilateral glands involved in the lymphatic drainage, as well as the cranial and caudal glands to the affected gland was performed. 19,20 A wide surgical margin of at least 3 cm around the tumor was performed in all cases. Skin margins were checked by histopathology in some cases and regional lymph nodes were excised in all cases.…”

Section: Mastectomymentioning

confidence: 99%

Effect of Adjuvant Perioperative Desmopressin in Locally Advanced Canine Mammary Carcinoma and its Relation to Histologic Grade

Hermo

Turic

Angelico

et al. 2011

Journal of the American Animal Hospital Association

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Desmopressin (DDAVP) is a vasopressin peptide analog with hemostatic properties that has been successfully used during surgery in patients with bleeding disorders. Recently published experimental and clinical data indicate that perioperative administration of DDAVP can minimize spread and survival of residual mammary cancer cells. The central aim of this study was to explore the effect of perioperative DDAVP and its relation to histologic grade in bitches with locally advanced mammary carcinoma. Of the 32 dogs initially recruited, 28 intact bitches with mammary carcinoma tumors stage III or IV were ultimately included. These dogs were randomized to receive DDAVP at intravenous doses of 1 μg/kg (n=18) or saline solution as placebo (n=10). En bloc mastectomy of the affected gland(s) was performed. Tumor malignancy was graded by the method of Elston and Ellis into well-differentiated (grade 1), moderately differentiated (grade 2), or poorly differentiated (grade 3). DDAVP therapy significantly prolonged the disease-free survival (P<0.001) and overall survival (P<0.01) in bitches with grade 2 or 3 carcinomas compared with bitches in the control group. No significant difference in disease-free period or overall survival was found between treatment groups in bitches with grade 1 tumors. The present data suggest that DDAVP may be an excellent candidate as a surgical adjuvant in the management of aggressive cancers in small animals. More research in this field is warranted.

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Section: Mastectomymentioning

confidence: 99%

Effect of Adjuvant Perioperative Desmopressin in Locally Advanced Canine Mammary Carcinoma and its Relation to Histologic Grade

Hermo

Turic

Angelico

et al. 2011

Journal of the American Animal Hospital Association

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“…Surgery remains the treatment of choice, possibly combined with hormonal, cytotoxic or radiation therapy (Wilkinson, 1971;Banks et al, 1972;Bostock and Owen, 1975;Gillete, 1987;Madewell and Theilen, 1987). The effects of various types of surgical excision have also been studied, but neither type has had a significant effect on the cancer-free interval (Allen and Mahaffey, 1989).…”

Section: Introductionmentioning

confidence: 99%

The Lymph Drainage of the Mammary Glands in the Bitch: a Lymphographic Study. Part I: The 1st, 2nd, 4th and 5th Mammary Glands

Patsikas

Dessiris

1996

Anat Histol Embryol

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The objective of this paper was to study the lymph drainage of the 1st, 2nd, 4th and 5th mammary glands in the bitch using indirect lymphography. The main conclusions drawn after the study of 67 normal lactating mongrel bitches were as follows: lymph drains from the first gland, usually to the axillary nodes, and, in few cases, to the axillary and superficial cervical nodes simultaneously. The second gland drains to the axillary nodes. The fourth gland usually drains to the superficial inguinal nodes, but it may, rarely, drain to the superficial inguinal and medial iliac nodes simultaneously. The fifth gland drains to the superficial inguinal nodes. Lymphatic connection between the mammary glands could not be demonstrated. Furthermore, it was confirmed that lymph can pass from one gland to another, through their common regional lymph nodes, by retrograde flow. It was demonstrated that there is a connection between the superficial inguinal lymph nodes from either side. It is suggested that lymphatic connection between the axillary and sternal nodes and between the axillary and bronchial nodes should be possible in some cases. Lymphatics of the mammary glands that cross the midline were not demonstrated.

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“…Ο Evans (1993) αναφέρει ότι τα λεμφαγγεία των μαστών του ενός στοίχου δε διαπερνούν τη μέση γραμμή για να ενωθούν με τα λεμφαγγεία των μαστών του άλλου στοίχου. Αντίθετα, άλλοι αναφέρουν ότι τα λεμφαγγεία, όπως και τα αιμοφόρα αγγεία, είναι δυνατό να διαπερνούν τη μέση γραμμή (Silver 1966, Wilkinson 1971, Christensen 1979, Johnston 1993, καθώς επίσης και το θωρακικό τοίχωμα (Silver 1966, Christensen 1979, Wilson 1981, Brodey και συν. 1983, Harvey 1985.…”

Section: ανατομική του λεμφικού συστήματοςunclassified

“…1983, Δεσίρης 1986). Επισημαίνεται ότι για να προσδιοριστούν ακτινολογικά οι μεταστατικές εστίες στους πνεύμονες πρέπει να είναι μεγαλύτερες από 0,5-lem (Wilkinson 1971, Brodey και συν. 1983).…”

Section: νεοπλασματων του μαστουunclassified

“…Οι μη προσεκτικοί χειρισμοί κατά τη διάρκεια της χειρουργικής επέμβασης, καθώς και πριν από αυτή, είναι δυνατό να αυξήσουν την πιθανότητα μετάστασης (Wilkinson 1971, Theilen 1975, Harvey 1983, Gilson και Stone 1990, Buracco 1992, Τσαγγάρης 1993).…”

Section: ιστολογικη ταξινομηση των νεοπλασματων του μαστουunclassified

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Συμβολη Στη Μελετη Της Θεραπειας Των Κακοηθων Νεοπλασματων Του Μαστου Στο Σκυλο

Καραγιαννοπουλου¹

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The treatment of mammary tumours in the bitch and a comparison with the cat

Cited by 8 publications

References 0 publications

Effect of Adjuvant Perioperative Desmopressin in Locally Advanced Canine Mammary Carcinoma and its Relation to Histologic Grade

Effect of Adjuvant Perioperative Desmopressin in Locally Advanced Canine Mammary Carcinoma and its Relation to Histologic Grade

The Lymph Drainage of the Mammary Glands in the Bitch: a Lymphographic Study. Part I: The 1st, 2nd, 4th and 5th Mammary Glands

Συμβολη Στη Μελετη Της Θεραπειας Των Κακοηθων Νεοπλασματων Του Μαστου Στο Σκυλο

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