The Treatment of Reflux Disease: Standard and Alternative Approach

Berzofsky, Craig; Sandhaus, Henya

doi:10.1007/978-3-030-48890-1_29

Cited by 3 publications

(3 citation statements)

References 71 publications

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“…Various types of synthetic gum-driven agents have been suggested so far. The ingredients that fight cavities include Ca phosphate [ 36 – 39 ] and bicarbonate [ 40 , 41 ]. They also include chlorhexidine [ 42 ] and copper chlorophyllin [ 43 ].…”

Section: Resultsmentioning

confidence: 99%

Chewing Gums as a Drug Delivery Approach for Oral Health

Banakar

Moayedi

Shamsoddin³

et al. 2022

International Journal of Dentistry

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Background. Drug delivery approaches with the shortest therapeutic period and the lowest side effects have always been considered a sublime target in the medical sciences. Among many delivery methods, chewing gum could be perceived as a promising drug carrier that can carry several types of drugs for oral health. These drug carriers could represent optimal therapeutic time and lower side effects due to their sustained release capability and lower required thresholds for the drug compared with other delivery approaches. The convenient use in the oral cavity’s local environment and the ability to locally carry multiple drugs are considered the main advantages of this delivery approach. Aim. This review aimed to explore chewing gum as a promising drug carrier that can carry several types of drugs for oral health. Materials and Methods. Articles were searched for on PubMed, ISI, SCOPUS, Google Patents, the Royal Society of Chemistry website, and electronic databases using MESH terms and the following keywords: (“Gum” OR “Chewing gum”) and (“Drug delivery OR Drug delivery systems”) in the English language. No time limit was applied, and all documents as of August 30th, 2020 were retrieved. Results. Gum-drug interactions, mechanisms of release, and formulations of the drugs might all play a role in this versatile delivery method. Accordingly, chewing gum-based carriers may be presented as a plausible candidate for drug delivery in oral diseases. Conclusion. Gum-driven drugs could be introduced as promising candidates for treating oral diseases due to their ability to deliver the proper local dosages of active ingredients, short contact time, biocompatibility, and biodegradable chemical structures.

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Section: Resultsmentioning

confidence: 99%

Chewing Gums as a Drug Delivery Approach for Oral Health

Banakar

Moayedi

Shamsoddin³

et al. 2022

International Journal of Dentistry

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“…[ 87 ] Reflux symptoms are believed to be caused by the belching of aerosolized gastric contents into the esophagus. [ 88 ]…”

Section: Impacts Of Covid-19 On Gerd Esophageal Mobility and Functionmentioning

confidence: 99%

Critical appraisal of how COVID-19 infection and imposed lockdowns have impacted gastroesophageal reflux: A review

Al-Momani,

Aolymat,

Al Haj Mahmoud

2024

Medicine

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Previous literature has demonstrated that COronaVIrus Disease of 2019 (COVID-19) impacts an individual gastrointestinal tract (GIT), causing symptoms like nausea, diarrhea, and loss of appetite. Severe acute respiratory syndrome coronavirus RNA has been discovered in the stool of infected individuals in earlier research. It was discovered that severe acute respiratory syndrome coronavirus was significantly expressed in the GIT, indicating that the virus can also infect the digestive system. Angiotensin-converting enzyme 2 functions as the viral receptor. The chronic illness known as gastroesophageal reflux disease (GERD) is typified by frequent reflux of stomach acid into the esophagus. By triggering the sensitized esophageal-bronchial neuronal circuit or aspirating into the airways (microaspiration), GER exacerbates respiratory diseases. Aspiration is a well-known risk to be considered when treating patients in intensive care units. Strong genetic correlations have been identified between COVID-19 infection and GERD susceptibility, suggesting a shared genetic basis for both conditions. Nonetheless, even though GERD, extraesophageal reflex, and COVID-19 have a number of significant risk factors and exhibit similar symptoms, the relationship between these illnesses has not yet been examined in depth. This review is the first of its kind to critically examine the association between the COVID-19 epidemic and GER and its associated diseases. The key objective of this work is to promote the creation of prevention plans, treatment plans, and guidelines while also enhancing and optimizing our understanding of the relationship between COVID-19 and GERs.

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“…Anti-reflux medications as well as modification of daily lifestyle are critical to the management of reflux laryngitis [ 10 ]. Patients with suspected LPR are advised to avoid stimuli that aggravate acid reflux, such as drinking alcohol, smoking, fatty foods, chocolate, acidic foods, spicy foods, and caffeine [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Current Knowledge and Practice of General Practitioners Towards Laryngopharyngeal Reflux in Saudi Arabia

Alrayah¹,

Alzahrani²,

Alghamdi³

et al. 2023

Cureus

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BackgroundGeneral practitioners (GPs) have a significant role in the diagnosis of patients with laryngopharyngeal reflux (LPR). Some published data revealed a lack of knowledge among GPs about the disease, consequently, this lack of knowledge impacted their performance. This survey aims to assess the current knowledge and practice of general practitioners regarding laryngopharyngeal reflux in Saudi Arabia. MethodologyThis survey study was conducted to assess the current knowledge and practice of general practitioners regarding laryngopharyngeal reflux in Saudi Arabia using an online questionnaire. The questionnaire was distributed and collected from the

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The Treatment of Reflux Disease: Standard and Alternative Approach

Cited by 3 publications

References 71 publications

Chewing Gums as a Drug Delivery Approach for Oral Health

Chewing Gums as a Drug Delivery Approach for Oral Health

Critical appraisal of how COVID-19 infection and imposed lockdowns have impacted gastroesophageal reflux: A review

Assessment of the Current Knowledge and Practice of General Practitioners Towards Laryngopharyngeal Reflux in Saudi Arabia

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