The trend of tuberculosis case notification and predictors of unsuccessful treatment outcomes in Samdrup Jongkhar district, Bhutan: A fourteen-year retrospective study

Penjor, Kinley; Kuenzang,; Tshokey, Tshokey; Wangdi, Kinley

doi:10.1016/j.heliyon.2021.e06573

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…Globally, tuberculosis has been ranked alongside Human Immunodeficiency Virus (HIV) infection as responsible for high morbidity and mortality, with an estimated 9.6 million incidence cases and 1.5 million mortalities in 2014 [4]. Infectious diseases of such nature put excessive burden on health systems and fragile economies of both low and middleincome countries [5] of which Ghana is no exception.…”

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confidence: 99%

Factors Affecting Tuberculosis Case Detection in Kwahu East District of the Eastern Region, Ghana - A Health Facility-Based Cross-Sectional Study among TB Patients

Kabiri¹,

Anthony²,

Kofi³

et al. 2022

J Infect Dis Epidemiol

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Introduction:Tuberculosis is ranked the second cause of mortalities in the world only behind the deadly COVID-19. The disease is very communicable especially in poorly ventilated environments and crowded places. High risk of transmission from patients to health workers and then to the general population has been a great worry for the tuberculosis control programme worldwide. While great efforts has been made to improve case detection and improve treatment outcomes using DOTS most districts in Africa still fall below the expected target. This study explored factors affecting TB case detection in Kwahu East District of the Eastern Region of Ghana. Methodology:A cross-sectional study involving 138 tuberculosis patients on treatment was used. A nonprobability sampling method (i.e., convenient sampling technique) was employed to study the TB patients due to the availability of the participants at the various treatment centres. A structured questionnaire was used to interview participants and the results analyzed using SPSS version 20.0. Data was presented in tables and figures in the form of descriptive statistics. Results:The result revealed that100 were males (72.46%) and 38 (27.54%) were females. The level of knowledge was above average (52.9%) among the TB patients. Majority of the TB patients reported to have suffered one form of stigmatization (weighted stigma score is 3.0). While the health facility remained the most reliable place for TB care most, TB cases reported they rather sought treatment from Prayer Camp (44.2%) as the number one choice. Reasons for choice of treatment place were distance (41.3%), cost (33.3%), belief of effective treatment outcome (10.1%) and shortage of medications (28.3%). Conclusion:In conclusion, the study revealed that knowledge about TB was above average. However, factors such as stigmatization, poor accessibility and shortage of medications affect TB case detection in the district. Conscious efforts should therefore be made to improve access, regular supply of medications and reduce stigmatization in the community and health facilities.

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Section: Introductionmentioning

confidence: 99%

Factors Affecting Tuberculosis Case Detection in Kwahu East District of the Eastern Region, Ghana - A Health Facility-Based Cross-Sectional Study among TB Patients

Kabiri¹,

Anthony²,

Kofi³

et al. 2022

J Infect Dis Epidemiol

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Factors determining successful treatment outcome among notified tuberculosis patients in Belagavi district of North Karnataka, India

Kumar,

Harakuni,

Paranjape

et al. 2024

Clinical Epidemiology and Global Health

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Treatment Outcome and Determinant Factors of Tuberculosis among Patients Treated at Bule Hora University Teaching Hospital, West Guji zone, southern Ethiopia

Aliyo Ali,

Tuke

2024

Preprint

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BACKGROUND: Tuberculosis (TB) is an infectious disease transmitted as an airborne disease. TB is still treatable even though it produces bacteria that are difficult to eradicate.. Early diagnosis and appropriate treatment are two clinical strategies recommended to prevent TB from spreading. OBJECTIVE: To determine trends in tuberculosis treatment outcomes and determinant factors among patients treated at Bule Hora University Teaching Hospital from January 2020 to December 2022. METHOD: An institutional-based retrospective cohort study was conducted at Bule Hora University Teaching Hospital to determine the treatment outcome among all patients treated for tuberculosis. The TB treatment register found at the TB clinic was reviewed to collect three-year treatment data on TB patients. The collected data consisted of demographic and clinical data comprising treatment outcomes. The data were entered and analyzed using the Statistical Package for Social Sciences (SPSS) version 20. Bivariate and multivariate logistic regression models were used for determinant analysis. The declaration of statistical significance was a P value less than 0.05. RESULT: The overall treatment success rate was 94.3% CI; 95% [90.9-97.8] of this half of the TB patients had cured their treatment, and 44.3% patients completed treatment. Of the unsuccessful treatment outcomes, 1.1% were failed treatment, 1.7% were lost to follow-up, and 2.9% died during the follow-up. Urban dwellers (AOR: 1.73; 95% CI: 1.02-2.68; P = 0.041) and HIV-negative individuals (AOR: 1.51; 95% CI: 0.95-4.90; P = 0.002) were determinants of successful TB treatment outcomes. The trend in the treatment success rate fluctuated, increasing from 2020 to 2021 and then slightly decreasing in 2022, while the death rate decreased from 2020 to 2022. CONCLUSION: The current treatment success rate exceeds the recommended target. However, special attention and strict follow-up are required for tuberculosis patients with a high risk of unsuccessful treatment outcomes, including rural residents and HIV status-positive patients, throughout their treatment period.

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The trend of tuberculosis case notification and predictors of unsuccessful treatment outcomes in Samdrup Jongkhar district, Bhutan: A fourteen-year retrospective study

Cited by 3 publications

References 29 publications

Factors Affecting Tuberculosis Case Detection in Kwahu East District of the Eastern Region, Ghana - A Health Facility-Based Cross-Sectional Study among TB Patients

Factors Affecting Tuberculosis Case Detection in Kwahu East District of the Eastern Region, Ghana - A Health Facility-Based Cross-Sectional Study among TB Patients

Factors determining successful treatment outcome among notified tuberculosis patients in Belagavi district of North Karnataka, India

Treatment Outcome and Determinant Factors of Tuberculosis among Patients Treated at Bule Hora University Teaching Hospital, West Guji zone, southern Ethiopia

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