The multifunctionality and sustainability of ecosystems are strongly dependent on their ability
to withstand and recover from disturbances—that is, ecosystem resilience (ER). However, the
dynamics and attributes of ER remain largely unknown, especially in China, where climatic
and anthropogenic pressures are high. In this study, we evaluated spatiotemporal patterns of
ER in China from 2001 to 2020 using solar-induced chlorophyll fluorescence. We estimated
the relative independent importance of climate change, CO2, and anthropogenic factors on
changes in ER signals. The results showed that more than half of the ecosystems in the study
area have experienced ER gain followed by ER loss during the past two decades. Before
breakpoints, climate change explained 58.29% of the ER change associated with increasing
precipitation. After breakpoints, 65.10% of the ER change was most affected by CO2, and
drought from rising temperature further deteriorated ER loss. We highlight that relationships
between changes in ER and climate are spatial heterogeneous and suggest increased negative
radiative effects of CO2, associated with global warming, on ecosystem stability due to the
saturated canopy photosynthesis. These findings have crucial implications for future climate
change mitigation, carbon peak, and carbon neutrality targets.