The Trifluoromethyl Group in Transition Metal Chemistry

Abstract

A general overview on trifluoromethyl–TM derivatives (TM = transition metal) is presented with special focus on those compounds that have been isolated or at least detected in solution. Representative examples have been selected in order to illustrate the main structural features and/or reactivity patterns.

The Versatile Behavior of Platinum Alkyne Complexes towards XeF2: Formation of Fluorovinyl and Fluorido Complexes

“…Therefore, only one molecule will be discussed. [99][100][101][102][103][104][105] It is likely that AgCF 3 is formed intermediately. [98] As expected, the bite angle P1-Pt1-N1o fc ompound 7 with 84.55(6)8 is smaller in comparison to the one in compound 3.T reatmento fc ompound 4 with AgF and CF 3 SiMe 3 under sonication led to the generation of the trifluoromethyl complex [Pt(PhC=CFPh)(CF 3 ){k 2 -(P,N)-iPr 2 PC 2 H 4 NMe 2 }] (8).…”

Reactions of organozinc reagents with potassium bromodifluoroacetate

“…A c c e p t e d M a n u s c r i p t 5 insertion of difluorocarbene into C-Zn bond or intermediate formation of difluorocarben-zinc complexes [16], they believed to be less likely.…”

Gold trifluoromethyl complexes

“…58 It is also noteworthy that the synthetic routes to simple complexes such as [Au(CF 3 ) x ] − (x = 2, 4) have been only recently reported. 70 In this Perspective, we have reviewed the synthesis, properties and reactivity of gold trifluoromethyl compounds, putting emphasis on recently reported reactions with potential synthetic interest. 67 This is of considerable interest, because reductive elimination is one of the key steps in metal mediated-or catalyzed coupling reactions and its activation barrier is usually very high for perfluoroalkyl complexes, limiting their applicability in this field.…”