Online healthcare supply chain management (OHCSCM) in rural areas is a matter of concern and is susceptible to policy changes, especially after the alarms raised by the COVID‐19 pandemic. This study aims to develop an approach towards examining the state and building a framework for examining the OHCSCM in rural areas. The study develops a framework by integrating various theories and methodologies like stakeholders' theory, critical success factor (CSF) theory, triple bottom line theory, fuzzy set theory, evidential reasoning approach, and scenario analysis for identifying the dynamism among the CSFs. The developed framework helps prioritize the CSFs based on environmental, economic, and social perspectives. Further, the model helps create scenarios for decision‐makers to improve the understanding of the CSFs influencing OHCSCM and achieve sustainability. The study reveals that infrastructure development, security and privacy of data, and use of predictive tools are the top factors that need immediate attention. By recognizing the interdependencies and interactions between these factors, managers can develop a more comprehensive and integrated approach to OHCSCM in rural areas. This understanding enables them to identify potential bottlenecks, streamline processes, and optimize resource allocation, ultimately saving valuable time and resources for achieving sustainability in the online healthcare supply chain in rural areas.