This introduction explains our vision, inclusion criteria, and mission for a curated issue about business communication and COVID-19. We focus on the big picture of communication agility lessons from a VUCA (volatility, uncertainty, complexity, and ambiguity) environment. We also present a definition and a typology of agile business communication, largely drawn from the papers in this collection. These manuscripts investigate COVID-19 organizational communication measures and related strategies plus their outcomes across diverse stakeholders in multiple countries. Drawing from these contributions and other research, we conclude by outlining an agile business communication research agenda. Finally we inaugurate a new IJBC column, Spotlight on a Thought Leader in Business Communication.