The Twente Photoacoustic Mammoscope: system overview and performance

Manohar, Srirang; Kharine, Alexei; Hespen, Johan C. G. van; Steenbergen, Wiendelt; Leeuwen, Ton G. van

doi:10.1088/0031-9155/50/11/007

Cited by 182 publications

(152 citation statements)

References 23 publications

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“…We have also provided specifications of various ultrasound detectors described in literature for comparison. The MDP value of our detector is 0.5 Pa, which is 160 times lower than for the detector used in the first generation of the Twente Photoacoustic Mammoscope previously developed in 415 our group [20]. To the best of our knowledge, this is the lowest measured MDP reported for a detector in photoacoustic breast imaging (Table III).…”

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confidence: 68%

An optimized ultrasound detector for photoacoustic breast tomography

et al. 2013

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15Purpose: Photoacoustic imaging has proven to be able to detect vascularization-driven optical absorption contrast associated with tumors. In order to detect breast tumors located a few centimeter deep in tissue, a sensitive ultrasound detector is of crucial importance for photoacoustic mammography. Further, because the expected photoacoustic frequency bandwidth (a few MHz to tens of kHz) is inversely proportional to the dimensions of light absorbing structures (0.5 to 10+ 20 mm), proper choices of materials and their geometries and proper considerations in design have to be made to implement optimal photoacoustic detectors. In this study, we design and evaluate a specialized ultrasound detector for photoacoustic mammography.Methods: Based on the required detector sensitivity and its frequency response, a selection of active material and matching layers and their geometries is made leading to a functional detector

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confidence: 68%

An optimized ultrasound detector for photoacoustic breast tomography

et al. 2013

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“…[59]). Array processing techniques have been used previously in medical applications includes ultrasonic imaging for fetal development monitoring and observation of the blood flow in the heart valves [60] and EEG signal processing for neurological disorders [61]. Both of these applications use the concept of beamforming [62], which estimates a signal from a specific sensor in a desired direction and separates signals from the remaining sensors from other directions.…”

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confidence: 99%

Spatial resolution in electrical impedance tomography: A topical review

Chitturi¹,

Nagi²

2017

Journal of Electrical Bioimpedance

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Electrical impedance tomography (EIT) is a relatively new imaging technique. It has the advantages of low cost, portability, noninvasiveness and is free from radiation effects. So far, this imaging technique has shown satisfactory results in functional imaging. However, it is not yet fully suitable for anatomical imaging due to its poor spatial resolution. In this paper, we review the basic directions of research in the area of the spatial resolution of the EIT systems. The improvements to the hardware and the software developments are highlighted. Finally, possible techniques to enhance the spatial resolution of the EIT systems using array processing beamforming methods are discussed.

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“…With such a system Khokhlova et al [9] were able to record a piece of liver with a diameter of 3 mm located at a depth of 2 cm in diluted milk. Manohar et al introduced the first Photoacoustic Mammoscope, applying parallel plate geometry where the breast is gently compressed between a glass plate and a flat ultrasound detector matrix [10]. However, despite their high sensitivity and the progress made in this field, piezoelectric detection systems still suffer from limited resolution and speed.…”

Section: Introductionmentioning

confidence: 99%

Detection of laser induced dielectric breakdown in water using a laser doppler vibrometer

et al. 2010

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Abstract:This study is focused on exploring the feasibility of an all-optic surface scanning method in determining the size and position of a submerged, laser generated, optoacoustic (OA) source. The optoacoustic effect in this case was generated when the absorption of a short electromagnetic pulse in matter caused a dielectric breakdown, a plasma emission flash and a subsequent acoustic wave. In the experiment, a laser pulse with λ = 1064 nm and 12 ns pulse length was aimed at a volume of deionized water. When the laser beam was focused by a = 16 mm lens, a single dielectric breakdown spot occurred. When a = 40 mm was used several breakdowns in a row were induced. The breakdowns were photographed using a double shutter camera. The acoustic wave generated by the dielectric breakdowns were detected at a point on the water surface using a laser Doppler vibrometer (LDV). First, the LDV signal was used to calculate the speed of sound with an accuracy of 10 m/s. Secondly, the location and length of the dielectric breakdown was calculated with an accuracy of 1 mm. The calculated position matched the breakdown location recorded by a camera. The results show that it is possible to use LDV surface measurements from a single spot to determine both the position and length of the OA source as well as the speed of sound in the medium. Furthermore, the LDV measurements also show a secondary peak that originates from the OA source. To unravel the origin and properties of this interesting feature, further investigations are necessary.

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The Twente Photoacoustic Mammoscope: system overview and performance

Cited by 182 publications

References 23 publications

An optimized ultrasound detector for photoacoustic breast tomography

An optimized ultrasound detector for photoacoustic breast tomography

Spatial resolution in electrical impedance tomography: A topical review

Detection of laser induced dielectric breakdown in water using a laser doppler vibrometer

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