The complex relationship between science and politics has been a perennial issue in public administration. In this debate it is important to distinguish between ‘good’ and ‘bad’ politics, and between ‘good’ and ‘bad’ science. The Covid-19 pandemic has valorised the importance of science in shaping governmental responses, and has tended to contrast politics negatively with science. However, technocratic approaches to policymaking downplay the importance of politics in policymaking. Two case studies, of countries where there have been markedly different pandemic outcomes are used to illustrate the relationship between science and politics during this public health crisis – New Zealand and Brazil. In New Zealand there has been a positive and effective, if technocratic, relationship between science and politics, while in Brazil the relationship between the two domains has been fraught.