The Types of Aloe species and their Multi-Function in Southern Ethiopia the Cases of Hammer District

Gebremedhin, Asmelash Tesfaye

doi:10.19080/ijesnr.2017.03.555619

Cited by 2 publications

(2 citation statements)

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“…It is extensively distributed in sub-Saharan Africa, Madagascar, and other islands of southern Africa. Forty-six Aloe species have been recognised in Ethiopia, 24 of which are endemic [25]. Barbosa et al [26] reported that the ascorbic acid found in Aloe Vera acts as a strong antibacterial agent that inhibits enzymatic activity and interferes with the bacterial genetic mechanism.…”

Section: Introductionmentioning

confidence: 99%

Experimental Investigation of Aloe Vera-Treated False Banana (Ensete Ventricosum) Fibre-Reinforced Polypropylene Composite

et al. 2023

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This research work investigates the effects of the concentration and treatment of chopped false banana (Ensete ventricosum) fibres on the mechanical properties of a polypropylene matrix. The chopped false banana fibres (FBFs) were modified using Aloe Vera gel following treatment with 5% NaOH for 12 h at room temperature, with 1% acetic acid used to neutralise the remaining NaOH. FBF-reinforced polypropylene composite plates were then manufactured with 10, 20, 30, and 40 wt.% of chopped FBF. The mechanical properties were investigated using the compressive, impact, and three-point bending tests. Regarding the mechanical properties of the FBF-reinforced polypropylene composites, it was found that they have a maximum average compressive strength of 17.2 MPa. A maximum bending strength of 12.109 MPa was found for the Aloe Vera gel-treated composite with 30 wt.% of FBF. The maximum average compressive strength for this composite was 17.19 MPa. A maximum bending strength of 9.97 MPa for untreated composites was recorded for the composite with 10 wt.% of FBF. Finally, Aloe Vera-treated FBF-reinforced composites have better mechanical properties than untreated ones. The mechanical properties of Aloe Vera-treated FBF-reinforced polypropylene composites, as determined via impact, compressive and flexural tests, were superior for composites with 30 wt.% of FBF.

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Section: Introductionmentioning

confidence: 99%

Experimental Investigation of Aloe Vera-Treated False Banana (Ensete Ventricosum) Fibre-Reinforced Polypropylene Composite

et al. 2023

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“…Therefore, safe, non-toxic, and cost-effective drugs are urgently required to eliminate this problem from every corner of world [7,17]. The latex of Aloe rugosifolia Gilbert & Sebsebe is traditionally used for treatments of malaria, wounds, worms, and internal parasites in human and livestock in Hamer district of southern Ethiopia [18]. Latexes of several Aloe species have been reported to possess antiprotozoal activity [19][20][21].…”

Section: Introductionmentioning

confidence: 99%

In Vitro Antileishmanial and Antitrypanosomal Activities of Plicataloside Isolated from the Leaf Latex of Aloe rugosifolia Gilbert & Sebsebe (Asphodelaceae)

et al. 2022

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Trypanosomiasis and leishmaniasis are among the major neglected diseases that affect poor people, mainly in developing countries. In Ethiopia, the latex of Aloe rugosifolia Gilbert & Sebsebe is traditionally used for the treatment of protozoal diseases, among others. In this study, the in vitro antitrypanosomal activity of the leaf latex of A. rugosifolia was evaluated against Trypanosoma congolense field isolate using in vitro motility and in vivo infectivity tests. The latex was also tested against the promastigotes of Leishmania aethiopica and L. donovani clinical isolates using alamar blue assay. Preparative thin-layer chromatography of the latex afforded a naphthalene derivative identified as plicataloside (2,8-O,O-di-(β-D-glucopyranosyl)-1,2,8-trihydroxy-3-methyl-naphthalene) by means of spectroscopic techniques (HRESI-MS, 1H, 13C-NMR). Results of the study demonstrated that at 4.0 mg/mL concentration plicataloside arrested mobility of trypanosomes within 30 min of incubation period. Furthermore, plicataloside completely eliminated subsequent infectivity in mice for 30 days at concentrations of 4.0 and 2.0 mg/mL. Plicataloside also displayed antileishmanial activity against the promastigotes of L. aethopica and L. donovani with IC50 values 14.22 ± 0.41 µg/mL (27.66 ± 0.80 µM) and 18.86 ± 0.03 µg/mL (36.69 ± 0.06 µM), respectively. Thus, plicataloside may be used as a scaffold for the development of novel drugs effective against trypanosomiasis and leishmaniasis.

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The Types of Aloe species and their Multi-Function in Southern Ethiopia the Cases of Hammer District

Cited by 2 publications

References 0 publications

Experimental Investigation of Aloe Vera-Treated False Banana (Ensete Ventricosum) Fibre-Reinforced Polypropylene Composite

Experimental Investigation of Aloe Vera-Treated False Banana (Ensete Ventricosum) Fibre-Reinforced Polypropylene Composite

In Vitro Antileishmanial and Antitrypanosomal Activities of Plicataloside Isolated from the Leaf Latex of Aloe rugosifolia Gilbert & Sebsebe (Asphodelaceae)

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