The ubiquity of neonicotinoid contamination: Residues in seabirds with different trophic habits

Distefano, Gabriele Giuseppe; Zangrando, Roberta; Basso, Marco; Panzarin, Lucio; Gambaro, Andrea; Ghirardini, Annamaria Volpi; Picone, Marco

doi:10.1016/j.envres.2021.112637

Cited by 25 publications

(8 citation statements)

References 44 publications

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“…Neonicotinoids were the subject of multi-residue analysis methods among other compounds [9,10]. Otherwise, they were targeted by specialized methods only tailored for multi-neonicotinoids [11][12][13][14][15] or a single compound, such as clothianidin [16], thiacloprid [17], and sulfoxaflor [18]. The methods mentioned earlier mainly used QuEChERS, modified QuEChERS, or QuEChERS, followed by DLLME (dispersive liquid-liquid microextraction).…”

Section: Introductionmentioning

confidence: 99%

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Development of Green and Facile Sample Preparation Method for Determination of Seven Neonicotinoids in Fresh Vegetables, and Dissipation and Risk Assessment of Imidacloprid and Dinotefuran

Abdallah,

Abd El-Hamid,

Ahmed

et al. 2024

Foods

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A facile procedure for extracting and determining seven neonicotinoids was developed. Water was the only extraction solvent without phase separation and cleanup steps. The method was validated according to European Union standards, and the values obtained were compared with the criteria. The accuracy values were between 99.8% (thiamethoxam) and 106.8% (clothianidin) at the spiking levels of 0.01, 0.1, and 1 mg/kg in the tested matrices. The precision as pooled RSD values was ≤6.1% (intra-day) and ≤6.9% (inter-day). The limit of quantification was set and tested at 0.01 mg/kg. The matrix effect was evaluated, and all matrices had a suppressive effect. The matrix of the cucumber was the most effective, with −20.9% for dinotefuran and an average of −9.8% for all compounds, while the tomato matrix had the slightest effect. Real marketed samples were analyzed using the developed and QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) methods; the results were not significantly different. A supervised field trial was conducted in the open field to study the dissipation patterns of imidacloprid and dinotefuran in tomatoes. The dissipation of both compounds followed first-order kinetics. The half-life (T½) values were 3.4 and 2.5 days, with dissipation rates k of 0.2013 and 0.2781 days, respectively. Following the EU-MRL database, the calculated pre-harvest interval (PHI) values were 7 and 14 days for imidacloprid and dinotefuran, respectively, and 3 days for both compounds following Codex Alimentarius regulations. The risk of imidacloprid and dinotefuran residues was estimated from chronic and acute perspectives. The risk factors of dinotefuran were lower than those of imidacloprid. Nonetheless, the highest expected residues of both compounds were below the tolerance limits.

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Section: Introductionmentioning

confidence: 99%

“…The methods mentioned earlier mainly used QuEChERS, modified QuEChERS, or QuEChERS, followed by DLLME (dispersive liquid-liquid microextraction). Various matrices were studied, such as environmental samples [12,19], animal tissues [9,10,13,15], and fresh crops [14,[16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Development of Green and Facile Sample Preparation Method for Determination of Seven Neonicotinoids in Fresh Vegetables, and Dissipation and Risk Assessment of Imidacloprid and Dinotefuran

Abdallah,

Abd El-Hamid,

Ahmed

et al. 2024

Foods

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“…20 Due to their systemic nature and widespread use, both the parent NNs and their degradation products have accumulated in the environment; for example, studies conducted in Europe showed that NNs were still present in the soil even ve years aer the moratorium, with no clear declining trend. 21 Globally, NNs have been found in 75% of honey samples, 5 in non-target species further up the food chain such as birds, 22,23 and perhaps not surprisingly then, are oen detected in human biological samples. [24][25][26][27] Therefore, NNs are a persistent threat to non-target species via continual exposure at sub-lethal concentrations.…”

Section: Introductionmentioning

confidence: 99%

Oxidation of solid thin films of neonicotinoid pesticides by gas phase hydroxyl radicals

Finlayson-Pitts

Anderson

Lakey

et al. 2023

Environ. Sci.: Atmos.

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“…Neonicotinoids (NEOs), a class of acetylcholine receptor inhibitors, are the most widely used pesticides, accounting for 30% of the global insecticide market and being registered in over 120 countries worldwide (Li et al 2022 ). Because of their advantages, such as high efficacy against sucking insects, ease of use, and low cost, they have gradually replaced organophosphorus, pyrethroid, and carbamate insecticides (Distefano et al 2022 ). NEOs are made up of seven compounds that are classified into three generations: the first (imidacloprid, nitenpyram, acetamiprid, and thiacloprid), the second (thiamethoxam and clothianidin), and the third (dinotefuran) (Li et al 2022 ).…”

Section: Introductionmentioning

confidence: 99%

The protective role of l-carnitine on oxidative stress, neurotransmitter perturbations, astrogliosis, and apoptosis induced by thiamethoxam in the brains of male rats

Abd Elkader,

Hussein,

Mohammed

et al. 2023

Naunyn-Schmiedeberg's Arch Pharmacol

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Synthetic organic insecticides such as pyrethroids, organophosphates, neonicotinoids, and others have the potential to disrupt ecosystems and are often toxic to humans. Thiamethoxam (TMX), a neonicotinoid insecticide , is a widely used insecticide with neurotoxic potential. l-Carnitine (LC) is regarded as the “gatekeeper” in charge of allowing long-chain fatty acids into cell mitochondria. LC is an endogenous chemical that is renowned for its prospective biological activity in addition to its role in energy metabolism. This study investigated the protective effects of LC against TMX-induced neurotoxicity in male Wistar rats. For 28 days, animals were divided into four groups and treated daily with either LC (300 mg/kg), TMX (100 mg/kg), or both at the aforementioned doses. Our results revealed marked serum lipid profile and electrolyte changes, declines in brain antioxidants and neurotransmitters (acetylcholine, dopamine, and serotonin levels) with elevations in thiobarbituric acid reactive substances and proinflammatory cytokine levels, as well as acetylcholinesterase and monoamine oxidase brain activity in TMX-treated rats. TMX also increased the expression of caspase-3 and glial fibrillary acidic protein. In contrast, pretreatment with LC attenuated TMX-induced brain injury by suppressing oxidative stress and proinflammatory cytokines and modulating neurotransmitter levels. It also ameliorated the expression of apoptotic and astrogliosis markers. It could be concluded that LC has antioxidant, anti-inflammatory, anti-astrogliosis, and anti-apoptotic potential against TMX neurotoxicity. Graphical abstract

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The ubiquity of neonicotinoid contamination: Residues in seabirds with different trophic habits

Cited by 25 publications

References 44 publications

Development of Green and Facile Sample Preparation Method for Determination of Seven Neonicotinoids in Fresh Vegetables, and Dissipation and Risk Assessment of Imidacloprid and Dinotefuran

Development of Green and Facile Sample Preparation Method for Determination of Seven Neonicotinoids in Fresh Vegetables, and Dissipation and Risk Assessment of Imidacloprid and Dinotefuran

Oxidation of solid thin films of neonicotinoid pesticides by gas phase hydroxyl radicals

The protective role of l-carnitine on oxidative stress, neurotransmitter perturbations, astrogliosis, and apoptosis induced by thiamethoxam in the brains of male rats

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