The UFS-QOL, a New Disease-Specific Symptom and Health-Related Quality of Life Questionnaire for Leiomyomata

Spies, James B.; Coyne, Karin S.; Guaou, Noureddine Guaou; Boyle, Deneane; Skyrnarz-Murphy, Kerry; Gonzalves, Sheila M.

doi:10.1097/00006250-200202000-00021

Cited by 167 publications

(229 citation statements)

References 9 publications

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“…Before treatment and at 6-and 12-month follow-up, patients were asked to complete an eight-item section of a uterine fibroid symptom and quality-of-life questionnaire to determine a symptom severity score (SSS) for leiomyoma-related symptoms (11)(12)(13)(14). Components were scored on a five-point Likert scale, with responses ranging from "not at all" to "a very great deal."…”

Section: Leiomyoma-related Symptom Assessmentmentioning

confidence: 99%

Uterine Leiomyomas: MR Imaging–guided Focused Ultrasound Surgery—Imaging Predictors of Success

Lénárd¹,

McDannold²,

Fennessy³

et al. 2008

Radiology

155

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Purpose:To retrospectively assess the magnetic resonance (MR) imaging predictors of success at reducing uterine leiomyoma volume and achieving patient symptom relief 12 months after MR imaging-guided focused ultrasound surgery. Materials and Methods:This single-center retrospective analysis of 71 symptomatic fibroids in 66 women was approved by the institutional review board and was HIPAA-compliant. Patients were treated with MR imaging-guided focused ultrasound surgery. The volume of treated fibroid and nonperfused volume (NPV) were calculated with software, while symptom outcome was assessed with a symptom severity score (SSS). Fibroids were classified as hyperintense or hypointense relative to skeletal muscle on pretreatment T2-weighted MR images. Results:Baseline volume of treated fibroids was 255.5 cm 3 Ϯ 201.7 (standard deviation), and baseline SSS was 61.5 Ϯ 14.9. Both pretreatment fibroid signal intensity (SI) and posttreatment NPV predicted 12-month volume reduction independently: Fibroids with an NPV of at least 20% or with low SI both showed significantly larger volume reduction (17.0% Ϯ 13.0 and 17.2% Ϯ 20.1, respectively) than fibroids with an NPV less than 20% or with high SI (10.7% Ϯ 18.2 and no significant change, respectively). Patients whose fibroids demonstrated an NPV of at least 20% also experienced a larger decrease in SSS than did patients with fibroids with an NPV less than 20% (50.1% Ϯ 19.8 vs 32.6% Ϯ 29.9). Conclusion:Fibroids with low SI on pretreatment T2-weighted MR images were more likely to shrink than were ones with high SI. The larger the NPV immediately after treatment, the greater the volume reduction and symptom relief were. These findings may help both in selecting appropriate patients for MR-guided focused ultrasound surgery and in predicting patient outcome.

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Section: Leiomyoma-related Symptom Assessmentmentioning

confidence: 99%

Uterine Leiomyomas: MR Imaging–guided Focused Ultrasound Surgery—Imaging Predictors of Success

Lénárd¹,

McDannold²,

Fennessy³

et al. 2008

Radiology

155

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“…The HRQL scale comprises the following subscales: concern, activities, energy/mood, control, self-consciousness and sexual function. 7 All answers have five options on a Likert scale. The higher the score on the severity subscale of the questionnaire is, the greater the severity of symptoms is; while the lower the scores on the HRQL subscales are, the poorer the quality of life is.…”

Section: Ufs-qol Questionnaire: Translation and Validationmentioning

confidence: 99%

“…Fourteen years ago, the only questionnaire directed towards UF, the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire, was published. 7 The responsiveness of this questionnaire was subsequently assessed 8 and it was validated in a non-randomized prospective study. 9 Thus, many studies that have investigated UF have been using this questionnaire.…”

Section: Introductionmentioning

confidence: 99%

Translation and validation of the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire for the Brazilian Portuguese language

et al. 2017

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CONTEXT AND OBJECTIVE: Uterine fibroids (UF), also known as leiomyomas, are the most prevalent gynecological tumors. The Uterine Fibroid Symptoms and Quality of Life (UFS-QOL) is the only specific questionnaire that assesses symptom intensity and quality-of-life issues for women with symptomatic UF; however, it only exists in the English language. Thus, we aimed to translate and culturally validate the UFS-QOL questionnaire for the Brazilian Portuguese language. DESIGN AND SETTING: Cross-sectional study, Department of Gynecology and Obstetrics, FMRP-USP. METHODS: 113 patients with UF (case group) and 55 patients without UF (control group) were interviewed using the UFS-QOL questionnaire after translation and cultural adaptation. The Short Form-36 questionnaire was used as a control. Demographic and psychometric variables were analyzed. RESULTS: Women with UF presented higher mean age, body mass index, weight, parity and comorbidities than the control group (P < 0.05). The most prevalent complaints were abnormal uterine bleeding (93.8%), pelvic pain (36.3%) and extrinsic compression (10.6%) and these presented adequate construct validity regarding UFS-QOL severity (P < 0.05). The UFS-QOL questionnaire presented good internal consistency regarding symptom severity and quality-of-life-related domains (intraclass correlation coefficient, ICC = 0.82/0.88). Structural validity presented correlation coefficients ranging from 0.59 to 0.91.

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“…The questionnaire established and used for this purpose, UFS-QoL (Uterine Fibroid Symptoms -Quality of Life), was developed specifically for myoma-related symptoms and evaluated for the minimally invasive treatment of symptomatic uterine fibroids and diseases with similar symptoms, such as uterine adenomyosis [13,14]. The symptom severity score (SSS), which specifies the severity of symptoms on a scale of 0 to 100 with high values indicating severe symptoms, was calculated with the help of the questionnaire.…”

Section: Symptom Reductionmentioning

confidence: 99%

MR-Guided HIFU Treatment of Symptomatic Uterine Fibroids Using Novel Feedback-Regulated Volumetric Ablation: Effectiveness and Clinical Practice

Ruhnke

Eckey

Bohlmann

et al. 2013

Fortschr Röntgenstr

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Purpose: To evaluate a novel feedback-regulated volumetric sonication method in MR-guided HIFU treatment of symptomatic uterine fibroids. Materials and Methods: 27 fibroids with an average volume of 124.9???139.8 cc in 18 women with symptomatic uterine fibroids were ablated using the new HIFU system Sonalleve (1.5?T MR system Achieva, Philips). 21 myomas in 13 women were reevaluated 6 months later. Standard (treatment) cells (TC) and feedback-regulated (feedback) cells (FC) with a diameter of 4, 8, 12, and 16?mm were used and compared concerning sonication success, diameter of?induced necrosis, and maximum achieved temperature. The non-perfused volume ratio (NPV related to myoma volume) was quantified. The fibroid volume was measured before, 1 month, and 6 months after therapy. Symptoms were quantified using a specific questionnaire (UFS-QoL). Results: In total, 205 TC and 227 FC were applied. The NPV ratio was 23???15?% (2???55). The TC were slightly smaller than intended (?3.9???52?%; range, ?100???81), while the FC were 20.1???25.3?% bigger (p?=?0.02). Feedback mechanism is less diversifying in diameter (p?

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The UFS-QOL, a New Disease-Specific Symptom and Health-Related Quality of Life Questionnaire for Leiomyomata

Cited by 167 publications

References 9 publications

Uterine Leiomyomas: MR Imaging–guided Focused Ultrasound Surgery—Imaging Predictors of Success

Uterine Leiomyomas: MR Imaging–guided Focused Ultrasound Surgery—Imaging Predictors of Success

Translation and validation of the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire for the Brazilian Portuguese language

MR-Guided HIFU Treatment of Symptomatic Uterine Fibroids Using Novel Feedback-Regulated Volumetric Ablation: Effectiveness and Clinical Practice

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