“…An important echocardiographic sign of severe PP is the failure to open the atrio-ventricular (AV) valve during systole, resulting in reduced left ventricular preload and LVSV. 46 PP is not present in all patients with cardiac tamponade. It may be absent in the presence of the following co-morbidities: atrial septal defect (ASD), 47,48 elevated left ventricular end-diastolic pressure, 49,50 aortic regurgitation, severe aortic stenosis, 51 regional tamponade, low-pressure cardiac tamponade, 52 pulmonary artery obstruction, 53 aortic dissection leading to hemopericardium, 11 extreme hypotension, 54 and severe musculoskeletal chest abnormalities.…”