The Ultrastructure of the Normal Conjunctival Epithelium of the Guinea Pig

Latkovic, Stefan; Nilsson, Sven Erik G.

doi:10.1111/j.1755-3768.1979.tb06666.x

Cited by 21 publications

(21 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because of its histological appearance, the conjunctiva was divided into four zones. Several authors graded the conjunctiva of guinea pigs, 13–18 rats, 19 and mice 20 in a different way to ours; however, in the study by Gasser et al. , 9 the zoning system in guinea pigs was reported similar to ours.…”

Section: Discussionsupporting

confidence: 62%

“…Because of its histological appearance, the conjunctiva was divided into four zones. Several authors graded the conjunctiva of guinea pigs, [13][14][15][16][17][18] rats, 19 and mice 20 in a different way to ours; however, in the study by Gasser et al, 9 the zoning system in guinea pigs was reported similar to ours. A limbal zone, defined by the presence of melanocytes within the basal layer of the epithelium, has been described in guinea pigs.…”

Section: Conjunctiva and Goblet Cellssupporting

confidence: 61%

“…Several solitary goblet cells may occur in the conjunctiva of chinchillas. Their density and distribution vary within different zones, as in guinea pigs; 9,14–18 t ‐test for independent samples was used to compare the mean goblet cell density of each conjunctival zone with those of the guinea pig (Table 4). In all four palpebral conjunctival zones, chinchillas revealed a significantly higher goblet cell density than guinea pigs, whereas the goblet cell density in all four bulbar zones is significantly higher in guinea pigs than in chinchillas (Table 4).…”

Section: Discussionmentioning

confidence: 99%

“…48 Nevertheless, frozen sections stained with Sudan red are necessary to verify the presence of lipids. Goblet cells Occurence Solitary Solitary 9, [14][15][16][17][18] In clusters 19,23 Not specified Solitary or in clusters 22…”

Section: Harderian Glandmentioning

confidence: 99%

“…Highest: palpebral Lowest: bulbar and marginal Highest: palpebral 9,16 Lowest: bulbar and limbal 9,14,15,17,18 Moderate to high: fornix 14,15,25 Highest: fornix 19 Lowest: bulbar and tarsal (palpebral) 19 Highest: fornix 20 Numerous: tarsal and bulbar Distributed throughout entire conjunctiva 22 g o b l e t c e l l s a n d o c u l a r g l a n d s i n t h e c h i n c h i l l a ⁽ c h i n c h i l l a l a n i g e r ⁾ 3 4 1 Myoepithelial cells, located between epithelial cells and the basement membrane of the alveoli, were found in the Octodon degu 48 and the species that are listed in Table 5, except in chinchillas. 34,41,43,44,46,47,51 It is likely that these cells may become visible in chinchillas using electron microscopy as described in gerbils.…”

Section: Density and Distributionmentioning

confidence: 99%

See 4 more Smart Citations

Investigations on the conjunctival goblet cells and the characteristics of the glands associated with the eye in chinchillas (Chinchilla Laniger)

Voigt

Fuchs‐Baumgartinger

Egerbacher

et al. 2012

Veterinary Ophthalmology

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 62%

Section: Conjunctiva and Goblet Cellssupporting

confidence: 61%

Section: Discussionmentioning

confidence: 99%

Section: Harderian Glandmentioning

confidence: 99%

Section: Density and Distributionmentioning

confidence: 99%

See 3 more Smart Citations

Investigations on the conjunctival goblet cells and the characteristics of the glands associated with the eye in chinchillas (Chinchilla Laniger)

Voigt

Fuchs‐Baumgartinger

Egerbacher

et al. 2012

Veterinary Ophthalmology

View full text Add to dashboard Cite

show abstract

Conjunctiva

Nichols

1996

Microsc. Res. Tech.

View full text Add to dashboard Cite

The conjunctiva is the mucous membrane that lines the inner surface of the eyelids and curves onto the anterior surface of the eyeball, where it extends to the cornea. It is continuous with the skin at the margin of the eyelids and with the cornea at the limbus (Wolff, 1976). Thus it forms a sac between the eyelids and the globe. Despite its small size, the conjunctiva plays a vital role in both vision and immunity. It physically protects the delicate structures of the eye by serving as a mechanical barrier to foreign substances, and it provides epithelium to cover corneal wounds (Kinoshita et al., 1983). Its goblet cells secrete mucus that forms the inner layer of the tear film and is essential for normal vision. The abundant blood supply of the conjunctiva delivers protective substances such as antibodies, complement, and white blood cells to the eye to combat infections and to remove dead or damaged tissue (Dawson, 1976, 1984). Lastly, the conjunctival, intestinal, bronchiolar, and other mucous membranes constitute the mucosal immune system (Chandler and Axelrod, 1980; Wolf and Bye, 1984), found in the regions of the body most commonly invaded by microorganisms. These topics will be discussed further in the following pages. When we began our study of the conjunctiva, our primary goal was to analyze the factors involved in the onset of an infection of the external eye. The surface of the epithelium, where invading microorganisms first impinge, had not yet been thoroughly investigated. We started by reexamining the structure of the normal epithelium and present here our observations of the structure of the conjunctiva, with emphasis on its surface. Of several species that we examined, the guinea pig most closely resembles man in conjunctival structure. Therefore, conjunctiva from pathogen‐free guinea pigs was used to illustrate this review. (See Technical Considerations.) © 1996 Wiley‐Liss, Inc.

show abstract