The United States Registry for Fibromuscular Dysplasia: Results in the First 447 Patients

Abstract

017). Including perioperative events at 2 years, there were no differences between groups in ipsilateral stroke, any stroke, disabling stroke, death, or any stroke or death.Comment: The study is interesting in that it suggests that the choice of CEA technique may influence periprocedural events but not long-term ipsilateral stroke or overall death. The limitations of this study are obvious: it used a nonrandomized post hoc analysis, with no information about why one CEA technique was chosen over the other, and lacked a blinded outcome assessment. The authors also note that an infinite hazard ratio confidence interval for ipsilateral stroke Ͼ30 days and the wide odds ratio confidence intervals for death rates indicate that, statistically, a substantial technique-dependent effect has not truly been ruled out by this study. Nevertheless, this was an independently monitored, multicenter study and therefore may have more generally applicable and accurate data than a single-center study.

Standing Waves Are Not Fibromuscular Dysplasia

“…We agree that the most frequent finding of fibromuscular dysplasia (FMD) in the coronary arteries is a distal tapering of the arteries and tortuosity (2). However, in the same reference that Drs.…”

Challenging Mimickers of Primary Systemic Vasculitis

“…1,2 This disease may occur in any age group, but mainly affects children and individuals more than 50 years of age. 3,4 The prevalence of FMD in the general population is estimated to be around 2% to 3%. 4,5 Women comprise up to 90% of cases in adults.…”

“…4,5 Women comprise up to 90% of cases in adults. 3,6 Approximately 10% of patients with FMD report a family member carrying the same diagnosis. 3,7 The most commonly affected vascular sites are middle and distal portions of the renal, internal carotid, and vertebral arteries (w65% of the cases).…”

“…3,6 Approximately 10% of patients with FMD report a family member carrying the same diagnosis. 3,7 The most commonly affected vascular sites are middle and distal portions of the renal, internal carotid, and vertebral arteries (w65% of the cases). 3 Lesions are detected less frequently in the intracranial, common carotid, external carotid, Box subclavian, coronary, mesenteric, iliac, and limb arteries.…”

Increased Prevalence of Preeclampsia among Women Undergoing Procedural Intervention for Renal Artery Fibromuscular Dysplasia

“…3e5 FMD affects women more commonly than men by a ratio of 9:1. 6 Although hormonal factors have been implicated in the pathophysiology of FMD because of its overwhelmingly female prevalence, the cause is unknown.…”