Extensional tectonics along NE-trending faults, coupled with diapirism, created paleo-highs and subsiding basins, providing the structural framework for subsequent mineralization processes. The preservation of organic matter within the Fahdene and Bahloul Cretaceous formations during the Anoxic Oceanic Events (AOE-1 and AOQ-2) facilitated the extraction of metals from seawater. The association of metals with organic matter, Fe-Mg oxides, and pyrite is revealed by principal component analysis (PCA). The subsequent maturation of organic matter generated hydrocarbons, with thermal cracking leading to the incorporation of organo-metallic ligands into mobile hydrocarbons. Oilfield brines form as a byproduct of this catagenesis. The metal-rich hydrocarbons and basinal brines invaded SO4−2-rich fluids from Triassic evaporites, resulting in the precipitation of sulfates (barite and celestite) and the bacteriogenic (BSR) and/or thermal (TSR) reduction of sulfate to reduced sulfur, which combined with metals to form sulfide ores. This study examines the role of hydrocarbons in the genesis of ore deposits within the diapiric zone, drawing upon a synthesis of literature and geological data. It highlights the interplay between basinal evolution, the organic matter-rich Cretaceous formations (Fahdene and Bahloul), diapiric paleo-highs, and the Alpine orogeny, which are identified as crucial factors in ore genesis in the diapiric zone.