The uptake of calcium-45 in the acellular-boned toadfish

Simmons, D. J.; Simmons, Neil; Marshall, J. H.

doi:10.1007/bf02017550

Cited by 30 publications

(14 citation statements)

References 41 publications

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“…The metabolic activity of acellular bone and its contribution to mineral regulation is a controversial topic. This has arisen as data exist for a number of different species suggesting that acellular bone is active (for a discussion, see Ekanayake and Hall 1987;Weiss and Watabe 1979), whereas other data suggest that it is inactive (Moss 1963;Mugiya and Watabe 1977;Simmons et al 1970). The large surface area to volume ratio and intimate contact observed between cells associated with the bone in the sea bream indicates the way that skeletal growth might continue throughout its lifecycle.…”

Section: Discussionmentioning

confidence: 89%

Cellular morphology and markers of cartilage and bone in the marine teleost Sparus auratus

et al. 2011

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Modifications have been characterised in terms of cellular organisation and the extracellular matrix (ECM) during bone ontogeny in the sea bream (Sparus auratus). During endochondral development, the agglomeration of matrix-secreting cells gives rise to chondrones; these chondrones frequently contain proliferating-cell-nuclear-antigen-positive cells, which subsequently become large collagen-II-positive cells with the characteristics of chondrocytes. Moreover, the matrix:cell ratio within the perichondrium increases, accompanied by a modification in ECM composition. Mineralisation of cartilage ECM is marked by a rapid fall in cell number, the switching off of collagen II transcription and the switching on of collagen X transcription, followed by collagen I transcription and bone mineralisation. The formation of dermal structures initiated upon the condensation of mesenchyme cells defines the future location of the dermal bone. Subsequent cellular differentiation gives rise to cells on the bone surface; these cells are positive for collagen I and osteonectin transcripts. The fish skeleton, with the exception of vertebrae, tends to comprise flattened bones that are covered by a monolayer of cells, the periosteum. A third type of tissue, present in gills, consists of chondrocyte-like cells embedded in a mineralised matrix resembling chondroid bone in mammals. The results suggest that the cellular organisation and ontogeny of endochondral and dermal bone in the sea bream are similar to those described in other vertebrates.

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Section: Discussionmentioning

confidence: 89%

Cellular morphology and markers of cartilage and bone in the marine teleost Sparus auratus

et al. 2011

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“…D'après MEUNIER (1982), ce processus a duré de 7 à 10 jours chez la carpe avant que la tétracycline administrée ait été absorbée. Cela indique que l'incorporation du marqueur est continue et lente (SIMMONS et al, 1970).…”

Section: Discussionunclassified

Nouvelle méthode de marquage vital d'oeufs de salmonidés par incorporation osmotique de tétracycline à la fécondation : expériences préliminaires sur des oeufs de truite fario (Salmo trutta fario)et de truites arc-en-ciel (Oncorhynchus mykiss)

Ruhlé¹,

Grieder

1989

Bull. Fr. Pêche Piscic.

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“…Acellular bone has been regarded as 'dead' bone (Moss, 1962), although osteoclasts do invade acellular bone (Glowacki et al, 1986;Sire et al, 1990;Weihs and Watabe, 1979;Witten, 1997). Nevertheless, the absence of canaliculi in acellular bone (Simmons et al, 1970) precludes an adaptive response of bone in the manner of the amniote cellular bone (Currey, 2002).…”

mentioning

confidence: 99%

Adaptive bone formation in acellular vertebrae of sea bass(Dicentrarchus labrax L.)

Kranenbarg

Cleynenbreugel

Schipper

et al. 2005

Journal of Experimental Biology

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SUMMARY Mammalian bone is an active tissue in which osteoblasts and osteoclasts balance bone mass. This process of adaptive modelling and remodelling is probably regulated by strain-sensing osteocytes. Bone of advanced teleosts is acellular yet, despite the lack of osteocytes, it is capable of an adaptive response to physical stimuli. Strenuous exercise is known to induce lordosis. Lordosis is a ventrad curvature of the vertebral column, and the affected vertebrae show an increase in bone formation. The effects of lordosis on the strain distribution in sea bass(Dicentrarchus labrax L.) vertebrae are assessed using finite element modelling. The response of the local tissue is analyzed spatially and ontogenetically in terms of bone volume. Lordotic vertebrae show a significantly increased strain energy due to the increased load compared with normal vertebrae when loaded in compression. High strain regions are found in the vertebral centrum and parasagittal ridges. The increase in strain energy is attenuated by a change in architecture due to the increased bone formation. The increased bone formation is seen mainly at the articular surfaces of the vertebrae, although some extra bone is formed in the vertebral centrum. Regions in which the highest strains are found do not spatially correlate with regions in which the most extensive bone apposition occurs in lordotic vertebrae of sea bass. Mammalian-like strain-regulated bone modelling is probably not the guiding mechanism in adaptive bone modelling of acellular sea bass vertebrae. Chondroidal ossification is found at the articular surfaces where it mediates a rapid adaptive response, potentially attenuating high stresses on the dorsal zygapophyses.

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The uptake of calcium-45 in the acellular-boned toadfish

Cited by 30 publications

References 41 publications

Cellular morphology and markers of cartilage and bone in the marine teleost Sparus auratus

Cellular morphology and markers of cartilage and bone in the marine teleost Sparus auratus

Nouvelle méthode de marquage vital d'oeufs de salmonidés par incorporation osmotique de tétracycline à la fécondation : expériences préliminaires sur des oeufs de truite fario (Salmo trutta fario)et de truites arc-en-ciel (Oncorhynchus mykiss)

Adaptive bone formation in acellular vertebrae of sea bass(Dicentrarchus labrax L.)

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