The Urinary System

Breshears, Melanie A.; Confer, Anthony W.

doi:10.1016/b978-0-323-35775-3.00011-4

Cited by 51 publications

(42 citation statements)

References 19 publications

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“…The outer medulla is the inner part of the cortex where the Henle loop and the collecting duct pass through. In dogs, CKD is known to be progressed by glomerulosclerosis and tubulointerstitial damage [ 23 24 ]. Therefore, it is more objective to assess the RCE focusing only on the cortex in CKD patients.…”

Section: Discussionmentioning

confidence: 99%

Can distinction between the renal cortex and outer medulla on ultrasonography predict estimated glomerular filtration rate in canine chronic kidney diseases?

et al. 2020

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Background: Quantitative evaluation of renal cortical echogenicity (RCE) has been tried and developed in human and veterinary medicine. Objectives: The objective of this study was to propose a method for evaluating RCE quantitatively and intuitively, and to determine associations between ultrasonographic renal structural distinction and estimated glomerular filtration rate (eGFR) in canine chronic kidney disease (CKD). Methods: Data were collected on 63 dogs, including 27 with normal kidney function and 36 CKD patients. Symmetric dimethylarginine and creatinine concentrations were measured for calculating eGFR. RCE was evaluated as 3 grades on ultrasonography images according to the distinction between the renal cortex and outer medulla. The RCE grade of each kidney was measured. Results: There was a significant difference in eGFR between the group normal and CKD (p < 0.001). As mean of RCE grades (the mean values of each right and left kidney's RCE grade) increases, the proportion of group CKD among the patients in each grade increases (p < 0.001). Also, severity of RCE (classified as "high" if any right or left kidney evaluated as RCE grade 3, "low" otherwise) and eGFR is good indicator for predicting group CKD (p < 0.001). Conclusions: The degree of distinction between the renal cortex and the outer medulla is closely related to renal function including eGFR and the RCE grade defined in this study can be used as a method of objectively evaluating RCE.

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Section: Discussionmentioning

confidence: 99%

Can distinction between the renal cortex and outer medulla on ultrasonography predict estimated glomerular filtration rate in canine chronic kidney diseases?

et al. 2020

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“…In general, most textbooks of veterinary medicine (Cianciolo & Mohr 2016, Breshears & Confer 2017, Serakides & Silva 2017 contain little, generic information on RCND, and this syndrome is mostly described in the international literature, with little information on its prevalence and presentation characteristics found in the national literature (Langohr et al 2002, Inkelmann et al 2012, which is important for the diagnosis and knowledge of the occurrence of this disease in the country.…”

Section: Introductionmentioning

confidence: 99%

Clinical-epidemiological, anatomic-pathological, histochemical and immunohistochemical characterization of renal cystadenocarcinoma-nodular dermatofibrosis syndrome in 11 German Shepherd dogs

et al. 2019

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Eleven cases of renal cystadenoma/cystadenocarcinoma-nodular dermatofibrosis syndrome (RCND) are described in German Shepherd dogs diagnosed from January 1994 to January 2018 at the Veterinary Pathology Laboratory of the “Universidade Federal de Santa Maria” (LPV-UFSM). The study sample was composed of eight male and three female dogs at a ratio of 2.67:1. Age ranged from six to 12 years (mean=8.7 years). The main clinical signs reported in descending order of frequency were multiple cutaneous nodules (nodular dermatofibrosis), dyspnea, anorexia, weight loss, recurrent hematuria, vomiting, and polydipsia. Results demonstrated that it is not always easy to clinically recognize this syndrome, but its peculiar anatomical-pathological characteristics allow safe diagnosis. Histologically, it was possible to detect all phases (cysts, papillary intratubular hyperplasia, and cystadenomas or cystadenocarcinomas) of a possible pathological continuum of the renal lesions. Uterine leiomyomas were observed in only one of the cases. Through histochemical techniques, it was possible to identify the presence of type I collagen in both cutaneous and renal lesions and consider its possible involvement in the pathogenesis of renal cystadenocarcinoma. Immunohistochemistry (IHC) showed partially satisfactory results in the staining of epithelial cells of renal cysts and neoplasms for pan-cytokeratin.

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“…Etiologically, the main causes of ARF can be summarized into three groups: physiologic, toxic, and infectious. Physiologic causes include renal ischemia due to hypovolemia, decreased cardiac output, increased blood viscosity, and altered renal and/or systemic vascular resistance [2, 5]. The list of toxic causes, especially in veterinary medicine, is exhaustive and ever expanding, and includes nephrotoxic medications such as antimicrobials, chemotherapy drugs, and NSAIDs as well as toxicants such as ethylene glycol, melamine, lead, toxic plants, excess vitamin D, excess hemoglobin from intravascular hemolysis, and excess serum myoglobin due to rhabdomyolysis [3, 6].…”

Section: Introductionmentioning

confidence: 99%

“…, and rickettsial diseases [3, 6, 7]. If the animal survives and the ARF leads to uremia, subsequent lesions may include stomatitis, glossitis, gastritis, pulmonary edema, fibrinous pericarditis, atrial thrombosis, coagulopathy, and soft tissue mineralization [2, 5].…”

Section: Introductionmentioning

confidence: 99%

Uremic encephalopathy in a rhesus macaque (Macaca mulatta): A case report and a brief review of the veterinary literature

Mustonen

González

Mendoza

et al. 2018

J of Medical Primatology

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The Urinary System

Cited by 51 publications

References 19 publications

Can distinction between the renal cortex and outer medulla on ultrasonography predict estimated glomerular filtration rate in canine chronic kidney diseases?

Can distinction between the renal cortex and outer medulla on ultrasonography predict estimated glomerular filtration rate in canine chronic kidney diseases?

Clinical-epidemiological, anatomic-pathological, histochemical and immunohistochemical characterization of renal cystadenocarcinoma-nodular dermatofibrosis syndrome in 11 German Shepherd dogs

Uremic encephalopathy in a rhesus macaque (Macaca mulatta): A case report and a brief review of the veterinary literature

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