The US prevalence of self-reported carpal tunnel syndrome: 1988 National Health Interview Survey data.

Background The most prominent nonneurological finding in the common compression neuropathy carpal tunnel syndrome (CTS) is fibrosis of the subsynovial connective tissue (SSCT). Recently, a rabbit model of CTS has been developed, based on the hypothesis that SSCT injury and subsequent fibrosis cause nerve compression. The purpose of this study was to evaluate the effects in this model at earlier and later time points than have heretofore been reported. Methods Sixty rabbits were operated on and observed at two different time periods: 6 and 24 weeks. Nerve electrophysiology (EP), SSCT histology, and SSCT mechanical properties were assessed. Results There was no significant difference in median motor nerve amplitude or latency at either time point. The total cell density in the SSCT was significantly higher at 6 and 24 weeks compared to controls. The mean size of the collagen fibrils in the SSCT was higher 6 and 24 weeks after surgery compared to controls. Both the ultimate load and the total energy absorption of the SSCT were significantly higher at 6 and 24 weeks compared to controls. Conclusions In this model, there were signs of SSCT fibrosis and histology changes at 6 weeks, which persist after 24 weeks. Thus, this model leads to sustained SSCT fibrosis, which is one characteristic of human CTS. However, no significant EP changes were found at these two time points, which is in contrast to the findings reported previously for this model at 12 weeks. The significance of the differences in EP findings will be the subject of future studies.

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“…Female rabbits were used because clinical CTS is more common in females [13]. Sixty rabbits had surgery, 30 each observed at 6 and 24 weeks.…”

Section: Methodsmentioning

confidence: 99%

The Effect of Time after Shear Injury on the Subsynovial Connective Tissue and Median Nerve within the Rabbit Carpal Tunnel

Vanhees

Chikenji

Thoreson

et al. 2012

Hand (New York, N,Y.)

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“…The number of participants utilized was small and their response to treatment may not be representative of the general population; however, our male to female ratio was similar to that of a previously published report. 22 The lack of a control does not permit us to conclude that our results would have been significantly different from time alone or placebo. Additionally, we were unable to directly compare our results with those of prior investigations as previous studies used various methodological designs, therapeutic procedures and outcome assessments.…”

Section: Discussionmentioning

confidence: 77%

The effects of active release technique on carpal tunnel patients: A pilot study

George

Tepe

Busold³

et al. 2006

Journal of Chiropractic Medicine

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“…As taxas de prevalência variam de acordo com a metodologia utilizada. Taxas de prevalência na população relatadas na literatura são de 0,15% 10 , 5,8% em mulheres e 0,6% em homens 19 e 1,55% 20 . A prevalência em uma população 25 a 74 anos, determinada clinica e eletrofisiologicamente, foi 2,7% 9 .…”

Section: Epidemiologia Epidemiologia Epidemiologia Epidemiologia Epidunclassified

Síndrome do túnel do carpo: controvérsias a respeito de diagnóstico clínico e eletrofisiológico e a relação com o trabalho

Oliveira

2000

Arq. Neuro-Psiquiatr.

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RESUMO -O diagnóstico de síndrome do túnel do carpo (STC) apresenta dificuldades porque dormência e formigamento nos membros superiores e alterações de condução nervosa no nervo mediano são comuns na população, havendo baixa concordância entre sintomas e alterações eletrofisiológicas. O diagnóstico de STC deve ser feito somente na presença de sintomas característicos acompanhados de alterações eletrofisiológicas significativas. Os casos duvidosos devem ser observados. A associação da STC com certas atividades é controversa.PALAVRAS-CHAVE: síndrome do túnel do carpo, exames eletrodiagnósticos, lesões por esforços repetitivos. Carpal tunnel syndrome: controversies regarding clinical and electrodiagnosis and its work-relatednessABSTRACT -The diagnosis of carpal tunnel syndrome (CTS) may be difficult because paresthesias and tingling in the upper limbs are commonly reported in the general population. These symptoms are poorly correlated with changes of nerve conduction studies of the median nerve. CTS should be diagnosed only when typical symptoms are associated with significant electrophysiological abnormalities. The association of CTS with work is highly controversial.KEY WORDS: carpal tunnel syndrome, electrodiagnostic tests, cummulative trauma disorders. Embora a síndrome do túnel do carpo (STC) seja comum, conhecida há mais de 100 anos 1 , frequentemente tratada cirurgicamente, causa importante de incapacidade para o trabalho e motivo de regulações extensas e dispendiosas do ambiente de trabalho 2,3 , ela é ainda cercada de controvérsias a respeito do seu diagnóstico e sua relação com o trabalho.O presente artigo é uma revisão crítica da literatura a respeito das controvérsias do seu diagnóstico e a relação com o trabalho, chamando a atenção para a complexidade do diagnóstico clínico e eletrofisiológico, geralmente apresentados como fatos bem estabelecidos e inquestionáveis. DIAGNÓSTICO DIAGNÓSTICO DIAGNÓSTICO DIAGNÓSTICO DIAGNÓSTICONão há critérios clínicos padronizados para o diagnóstico de STC 4,5 , não havendo consenso universal se o diagnóstico deve ser feito em bases clínicas ou eletrofisiológicas 6-9 . Uma reunião de 12 especialistas concluiu por consenso que a STC deve ser definida como síndrome eletroclínica 6 , O quadro clínico é caracterizado por parestesias (formigamento) progressivas na mão, no início noturnas e posteriormente com duração mais prolongada, que desaparecem com movimentos da mão. As parestesias são localizadas na palma da mão e dedos mas o paciente pode relatar sintomas dolorosos

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The US prevalence of self-reported carpal tunnel syndrome: 1988 National Health Interview Survey data.

Cited by 176 publications

References 6 publications

The Effect of Time after Shear Injury on the Subsynovial Connective Tissue and Median Nerve within the Rabbit Carpal Tunnel

The Effect of Time after Shear Injury on the Subsynovial Connective Tissue and Median Nerve within the Rabbit Carpal Tunnel

The effects of active release technique on carpal tunnel patients: A pilot study

Síndrome do túnel do carpo: controvérsias a respeito de diagnóstico clínico e eletrofisiológico e a relação com o trabalho

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