Objective: The purpose of this study was to compare between the effects of clinically supervised exercises and HEP on pain, disability and physical function in patients with chronic low back pain (LBP). Setting: A physical therapy outpatient clinic. Participants: Thirty-three participants with chronic LBP completed the program. Pain duration was more than 12 weeks. Interventions: The first group (n=17, mean age=41.5±13.5 years) received clinically supervised exercises and HEP. The second group (n=16, mean age=44.2±15.6 years) received HEP. Materials: Visual analogue scale, Oswestry disability questionnaire and performance based measures (the fifty-foot preferred speed walk, fifty-foot fast walk, and distance walked in five minutes) were used to measure pain, disability and physical function before and after 6 weeks of intervention.