2017
DOI: 10.4103/psychiatry.indianjpsychiatry_34_17
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The use and effectiveness of pro re nata psychotropic medications in children and adolescents: A systematic review

Abstract: Background:Published studies have not demonstrated the benefits of the practice of psychotropic PRN administration.Aim:The goal of this study is to perform a systematic review on pro re nata (PRN) psychotropic medications administration in children and adolescents and examine the safety and effectiveness of this practice in child and adolescent psychiatric care units.Settings and Design:This is a systematic review.Materials and Methods:Several databases were searched till date. One hundred and sixty-five title… Show more

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Cited by 7 publications
(2 citation statements)
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“…The high rate of PRN prescription and administration highlights the need for developing appropriate strategies for ensuring safe and appropriate PRN medicines management [ 37 ], especially given the current lack of relevant evidence-based clinical guidelines and instructions for practice at both national and international level [ 45 ]. PRN medicines form a significant proportion of medication errors, at between 9–40% in intensive care units; furthermore, PRN medications are especially likely to contribute to medical errors [ 34 , 46 , 47 , 48 ]. This is significant, given that over 90% of patients with psychiatric disorders receive at least one PRN medication [ 33 ]; 20–86% of nursing home residents receive some PRN drug administration [ 36 , 49 ]; and in outpatient clinics, the prevalence rate is about 77% [ 50 ].…”
Section: Prn Medicationmentioning
confidence: 99%
“…The high rate of PRN prescription and administration highlights the need for developing appropriate strategies for ensuring safe and appropriate PRN medicines management [ 37 ], especially given the current lack of relevant evidence-based clinical guidelines and instructions for practice at both national and international level [ 45 ]. PRN medicines form a significant proportion of medication errors, at between 9–40% in intensive care units; furthermore, PRN medications are especially likely to contribute to medical errors [ 34 , 46 , 47 , 48 ]. This is significant, given that over 90% of patients with psychiatric disorders receive at least one PRN medication [ 33 ]; 20–86% of nursing home residents receive some PRN drug administration [ 36 , 49 ]; and in outpatient clinics, the prevalence rate is about 77% [ 50 ].…”
Section: Prn Medicationmentioning
confidence: 99%
“…There are research gaps regarding the patient safety concerns among the outpatients using psychotropic PRN medications. Systematic reviews on psychotropic PRN medications have suggested that qualitative approach among mental health patients is needed, which might address the medication-related problems (4,18,19). Hence, to focus on these issues, there is a need for a qualitative study among the patients using psychotropic PRN medications in outpatient settings.…”
Section: Introductionmentioning
confidence: 99%