“…Furthermore, intraoperative intolerance of prolonged single-lung ventilation as well as the perioperative impossibility of adequately placing the bronchus blocker-especially in the case of extensive procedures requiring complex multiple vessel revascularization-may lead to either conversion to full sternotomy or need for cardiopulmonary bypass, usually through femoral cannulation, both of which may be harmful to the patient, for example, by the additional wound trauma or potential atheromatous aorta with increased risk of stroke. Hence, optimal ventilation strategies for MICS-CABG procedures have already been widely discussed in the past [14][15][16], with, however, conventional single-lung ventilation still being the standard approach.…”