The use of a distal occlusion balloon protection device in acute coronary syndrome

Li, Steven S.‐L.; Lam, C.W.; So, Y.C.; Wong, Cheuk-Kit; Yiu, Siu Fung; Ho, Dsw; Chan, Kamtim; Chan, KK

doi:10.1016/s0167-5273(03)00097-4

Cited by 9 publications

(12 citation statements)

References 10 publications

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“…Finally, the atheroembolism during the revascularization procedure may add to the extent of myocardial damage [9]. To optimize the salvage of infarct myocardium with revascularization, many trials have aimed at reducing the atheroembolic injury using a variety of innovative devices to filter these microemboli [10][11][12]. The present study was also designed with this concept in mind.…”

Section: Discussionmentioning

confidence: 99%

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Distal protection device protects microvascular integrity during primary percutaneous intervention in acute myocardial infarction: A prospective, randomized, multicenter trial

Tahk¹,

Choi²,

Choi³

et al. 2008

International Journal of Cardiology

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Section: Discussionmentioning

confidence: 99%

“…Several recent studies have suggested that mechanical distal protection during primary angioplasty in patients with AMI may improve angiographic and clinical outcomes [10][11][12]. But distal embolization and prevention of it during revascularization procedure is nevertheless the subject of recent controversy.…”

Section: Introductionmentioning

confidence: 99%

Distal protection device protects microvascular integrity during primary percutaneous intervention in acute myocardial infarction: A prospective, randomized, multicenter trial

Tahk¹,

Choi²,

Choi³

et al. 2008

International Journal of Cardiology

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“…However, ''slow-flow'' and ''no-reflow'' phenomena occur commonly during percutaneous coronary intervention (PCI). These phenomena are characterized by reduced epicardial blood flow without apparent vessel obstruction [1][2][3][4]. Microvascular obstruction is frequently implicated as the underlying cause.…”

Section: Introductionmentioning

confidence: 99%

“…Microvascular obstruction is frequently implicated as the underlying cause. Increasing evidence has suggested that plaque burden or platelet thrombi play a crucial role in embolization in the microvasculature [2,3]. Treatment of ''slow-flow'' or ''no-flow'' can be difficult, and the best treatment of distal embolization is to prevent its occurrence.…”

Section: Introductionmentioning

confidence: 99%

“…DPDs are used for transient distal balloon occlusion during angioplasty or stent placement, and allowed recovery of any liberated plaque by aspiration before restoration of the antegrade flow. Initial work with DPDs has demonstrated consistent recovery of plaque (cholesterol crystals, foam cells, fibrous plaque) that otherwise would have embolized into the myocardial bed [2][3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

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Effects of distal protection on left ventricular function in acute anterior myocardial infarction: a Doppler echocardiographic study

Duan

Zhang

Liu

et al. 2009

Int J Cardiovasc Imaging

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Whether distal protection devices (DPDs) during percutaneous coronary intervention (PCI) can improve myocardial function in patients with acute myocardial infarction (AMI) is still under debate. Using tissue Doppler imaging (TDI), we evaluate the global and regional left ventricular systolic and diastolic functions in patients with anterior AMI using DPDs compared with conventional PCI. Ninety-six patients with anterior AMI were randomly assigned to either PCI with DPDs (DPD, n = 46) or traditional PCI (control, n = 50) groups. At the 3- and 6-month follow-ups, the DPD group had a higher left ventricular ejection fraction than the control group (51.6 +/- 3.6 vs. 49.3 +/- 5.3% and 53.0 +/- 3.7 vs. 50.8 +/- 5.2%, respectively; both P < 0.05). Moreover, peak systolic (S (a)) and early diastolic (E (a)) mitral annular velocities obtained by TDI were significantly higher in the DPD group than in the control group (S (a): 7.57 +/- 0.53 vs. 7.12 +/- 0.62 cm/s and 7.71 +/- 0.63 vs. 7.32 +/- 0.59 cm/s; E (a): 7.23 +/- 0.78 vs. 6.89 +/- 0.86 cm/s and 7.49 +/- 0.69 vs. 7.04 +/- 0.85 cm/s, respectively; all P < 0.05). However, systolic and diastolic regional myocardial velocities significantly improved in the DPD group from the 1-month follow-up compared with those in the control group (all P < 0.05). Patients who received treatment with DPDs experienced enhanced improvement of cardiac function. Thus, anterior AMI patients can benefit from DPDs during PCI.

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Distal Microcirculatory Protection During Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

Stone

Webb

Cox³

et al. 2005

JAMA

510

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for the Enhanced Myocardial Efficacy and Recovery by Aspiration of Liberated Debris (EMERALD) Investigators M YOCARDIAL SALVAGE IS frequently suboptimal after percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI), and mortality remains excessive in highrisk subgroups. 1-4 Despite normal epicardial Thrombolysis in Myocardial Infarction (TIMI) flow after primary PCI, myocardial perfusion (as assessed either by angiographic capillary opaci-fication [myocardial blush] or electrocardiographic ST-segment resolution [STR]) is abnormal in a significant proportion of patients, contributing to For editorial comment see p 1116.

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The use of a distal occlusion balloon protection device in acute coronary syndrome

Cited by 9 publications

References 10 publications

Distal protection device protects microvascular integrity during primary percutaneous intervention in acute myocardial infarction: A prospective, randomized, multicenter trial

Distal protection device protects microvascular integrity during primary percutaneous intervention in acute myocardial infarction: A prospective, randomized, multicenter trial

Effects of distal protection on left ventricular function in acute anterior myocardial infarction: a Doppler echocardiographic study

Distal Microcirculatory Protection During Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

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