The Use of Acupuncture with <i>In Vitro</i> Fertilization as a Treatment for Female Subfertility

Weeks, Katie; Gaspard, Gracie

doi:10.1089/acm.2012.0468

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…4 Acupuncture, as an effective non-pharmacological therapy, has been chosen by many infertile couples undergoing infertility treatment. 3,[5][6][7][8] It is reported that "fertility problems" is the second most common health condition for which people choose acupuncture treatment in the UK. 9 Acupuncture could improve the reproductive outcomes of IVF.…”

Section: Introductionmentioning

confidence: 99%

Transcutaneous Electrical Acupoint Stimulation Improves the Outcomes of In Vitro Fertilization: A Prospective, Randomized and Controlled Study

Wang

et al. 2017

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Section: Introductionmentioning

confidence: 99%

Transcutaneous Electrical Acupoint Stimulation Improves the Outcomes of In Vitro Fertilization: A Prospective, Randomized and Controlled Study

Wang

et al. 2017

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Effects of acupuncture during in vitro fertilization or intracytoplasmic sperm injection: An updated systematic review and meta-analysis

Zhang

Lee

Smith

et al. 2018

European Journal of Integrative Medicine

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Acupuncture in improving endometrial receptivity: a systematic review and meta-analysis

Zhong

Zeng

Liu

et al. 2019

BMC Complement Altern Med

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BackgroundThis systematic review aimed at summarizing and evaluating the evidence of randomized controlled trials (RCTs) using acupuncture to improve endometrial receptivity (ER).MethodsWe searched 12 databases electronically through August 2018 without language restrictions. We included RCTs of women of infertility due to low ER, and excluded infertility caused by other reasons or non-RCTs. Two independent reviewers extracted the characteristics of studies and resolved the differences through consensus. Data were pooled and expressed as standard mean difference (SMD) or mean difference (MD) for continuous outcomes and risk ratio (RR) for dichotomous outcomes, with 95% confidence interval (CI).ResultsWe found very low to moderate level of evidence that acupuncture may improve pregnancy rate (RR = 1.23 95%CI[1.13, 1.34] P < 0.00001) and embryo transfer rate (RR = 2.04 95%CI[1.13, 3.70] P = 0.02), increase trilinear endometrium (RR = 1.47 95%CI [1.27, 1.70] P < 0.00001), thicken endometrium (SMD = 0.41 95% CI [0.11, 0.72] P = 0.008), reduce resistive index (RI) (MD = -0.08 95% CI [− 0.15, − 0.02] P = 0.01), pulse index (PI) (SMD = -2.39 95% CI [− 3.85, − 0.93] P = 0.001) and peak systolic velocity/ end-diastolic blood velocity (S/D) (SMD = -0.60 95% CI [− 0.89, − 0.30] P < 0.0001), compared with medication, sham acupuncture or physiotherapy. Acupuncture was statistically significant as a treatment approach.ConclusionThe efficacy and safety of acupuncture on key outcomes in women with low ER is statistically significant, but the level of most evidence was very low or low. More large-scale, long-term RCTs with rigorous methodologies are needed.

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The Use of Acupuncture with In Vitro Fertilization as a Treatment for Female Subfertility

Cited by 3 publications

References 5 publications

Transcutaneous Electrical Acupoint Stimulation Improves the Outcomes of In Vitro Fertilization: A Prospective, Randomized and Controlled Study

Transcutaneous Electrical Acupoint Stimulation Improves the Outcomes of In Vitro Fertilization: A Prospective, Randomized and Controlled Study

Effects of acupuncture during in vitro fertilization or intracytoplasmic sperm injection: An updated systematic review and meta-analysis

Acupuncture in improving endometrial receptivity: a systematic review and meta-analysis

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