The presented paper examines the integration of Artificial Intelligence (AI) in the management of smart cities, focusing on the Silesian and Lesser Poland Voivodships in Poland. This research addresses a notable gap in the analysis of regional AI strategies within urban management, providing a comparative analysis of AI implementation in these two distinct regions. The Silesian Voivodship, with its emphasis on traditional industries such as manufacturing and energy, contrasts with the broader approach of the Lesser Poland Voivodship, which includes applications in life sciences and ICT. The paper explores how AI technologies enhance urban efficiency, sustainability, and livability through practical applications in traffic management, healthcare, energy efficiency, and environmental management. It highlights the importance of a human-centric approach in smart city development, emphasizing inclusivity, transparency, and ethical considerations. The paper also delves into the socio-technical dynamics of AI deployment, illustrating how these technologies can transform urban environments while ensuring that the benefits are equitably distributed and that urban developments are sustainable and resilient. By analyzing specific case studies, the authors aim to provide empirical evidence and insights that contribute to the academic and practical understanding of AI’s role in smart cities, ultimately advocating for the design of AI applications that prioritize human well-being and environmental health.