The Use of Antidepressant Drugs and the Lifetime Prevalence of Major Depressive Disorders in Italy

Carta, Mauro Giovanni; Aguglia, Eugenio; Bocchetta, Alberto; Balestrieri, Matteo; Caraci, Filippo; Casacchia, M; Dell’Osso, Liliana; Sciascio, Guido Di; Drago, Filippo; Faravelli, Carlo; Lecca, Maria Efisia; Moro, Maria Francesca; Morosini, Pier Luigi; Nardini, Marcello; Palumbo, Gabriella; Hardoy, Maria Carolina

doi:10.2174/1745017901006010094

Cited by 61 publications

(94 citation statements)

References 13 publications

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“…The SF-12 score was dichotomized by subdividing the sample on the basis of score distribution (p or 4 36), taking into account the characteristics of the previously published Italian community sample. 11,23 The same subdivision was used for the Argentine distribution.…”

Section: Discussionmentioning

confidence: 99%

“…11,12 In bried, controls were randomly drawn from municipal records of the adult population in seven different areas of Italy, including several localities with wide variations in socioeconomic conditions. The regions of Sicily, Sardinia, and Puglia in the South, Tuscany and Abruzzo in central Italy, and Friuli-Venezia Giulia in the North were included.…”

Section: Samplementioning

confidence: 99%

“…The scoring allows formulation of two health indices: physical and psychological state. The Advanced Neuropsychiatric Tools and Assessment Schedule (ANTAS-SCID), 11 a semi-structured clinical interview partially derived from the Structured Clinical Interview I for DSM-IV (SCID-I), 21 was used to test for psychiatric disorders. This interview was administered by a trained clinician to 40 randomly selected individuals (positive and negative at MDQ) for quality control of screening accuracy.…”

Section: Toolsmentioning

confidence: 99%

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An evolutionary approach to mania studying Sardinian immigrants to Argentina

Carta

Perra

Atzeni

et al. 2017

Rev. Bras. Psiquiatr.

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Objective: To ascertain lifetime prevalence of positivity to a screening questionnaire for bipolar disorders (BD) in Sardinian immigrants to Argentina and residents of Sardinia and assess whether such positivity affects quality of life (QoL) in either group. Our hypothesis is that screen positivity for BD may be more frequent in immigrants. Methods: Observational study. Subjects were randomly selected from the membership lists of associations of Sardinian immigrants in Argentina. A study carried out in Sardinia using the same methodology was used for comparison. The Mood Disorder Questionnaire was used to screen for mania/hypomania and the Short-Form Health Survey-12 to measure QoL. Results: A higher prevalence of manic/hypomanic episodes was found in Sardinian immigrants to Argentina (p o 0.0001; odds ratio = 3.0, 95% confidence interval 1.87-4.77). Positivity at screening was associated with a lower QoL both in Sardinian immigrants to Argentina and in residents of Sardinia. Conclusions: To the best of our knowledge, this is the first study to show a higher lifetime prevalence of manic/hypomanic episodes in a general-population sample of individuals who migrated to a foreign country. Our results are in agreement with the hypothesis that hyperactive/novelty-seeking features may represent an adaptive substrate in certain conditions of social change.

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Section: Discussionmentioning

confidence: 99%

Section: Samplementioning

confidence: 99%

Section: Toolsmentioning

confidence: 99%

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An evolutionary approach to mania studying Sardinian immigrants to Argentina

Carta

Perra

Atzeni

et al. 2017

Rev. Bras. Psiquiatr.

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“…The psychiatric interviews were conducted by means of the “Advanced Neuropsychiatric Tools and Assessment Schedule” (ANTAS) [17]. A semi-structured clinical interview derived in part from the SCID-I non-patient version (SCID-I/NP) [18] was used to assess the presence of psychiatric disorders according to the ICD-10 diagnosis [13].…”

Section: Methodsmentioning

confidence: 99%

Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder

Sancassiani¹,

Carta²,

Montisci³

et al. 2018

CPEMH

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Background:The aim was to study the association between mood and anxiety disorders and the Tako-Tsubo Syndrome (TTS) and to determine the role of antidepressants and the impairment of quality of life due the comorbid psychiatric disorder.Methods:Case-control study: 19 consecutive patients (17 female) with TTS compared to 76 controls without TTS, were randomly selected from the database of a nationwide epidemiological study after matching (gender, age and residence) by controls. Psychiatric diagnoses were carried out according to the ICD-10 using semi-structured interview tools (ANTAS-SCID) administered by clinical staff. Quality of Life (Qol) was assessed by means of SF-12.Results:Only Major Depressive Disorders (MDD) showed higher frequencies in cases with statistical significance difference (p=0.014) as well as at least one Mood Disorder Diagnosis [MDD or BD] (p=0.002). The lifetime prevalence of at least one anxiety disorder with no comorbid mood disorder did not show a higher frequency in cases (p=0.57).The score at SF-12 in the TTS group was similar to those of controls (p=0.71)In the TTS group, the score at SF-12 in people with one mood or anxiety diagnosis (N=7) was similar to those without mood or anxiety diagnosis (p=0.75). The use of antidepressants was higher in TTS group (15.79% vs 1.31%; p=0.030).Conclusion:The study shows an association between TTS with depressive disorders and antidepressants use and does not confirm the association with anxiety syndromes. The study suggests the need to investigate the possible interactions between antidepressants use and mood disorders in studies with appropriate design and sample size.

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“…A form was to be filled in to record sociodemographic data, health service utilization and risk factors [4]; the study adopted the nonpatient version of the SCID-I-DSM-IV [4] and the Italian version of the 20-item Toronto Alexithymia Scale (TAS-20) [5], a self-reporting checklist measuring the ability to identify and describe feelings and to distinguish between feelings and bodily sensations. Alexithymic trait scores were characterized using established classification scores (scores ≥61).…”

Section: Tablementioning

confidence: 99%