The use of antimicrobial agents in broiler chickens

Landoni, M. F.; Albarellos, G. A.

doi:10.1016/j.tvjl.2015.04.016

Cited by 104 publications

(85 citation statements)

References 51 publications

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“…Drug elimination is mainly via feces and urine; therefore, the habit of coprophagy among broilers may increase the depletion time of the drugs, supporting a withdrawal period of 10 days [43]. However, in the present study, the need for compliance with this long withdrawal period was not evident because concentrations lower than the LOQ of the method were observed by the fourth day after the end of treatment.…”

Section: Resultsmentioning

confidence: 59%

Evaluation of the Presence and Levels of Enrofloxacin, Ciprofloxacin, Sulfaquinoxaline and Oxytetracycline in Broiler Chickens after Drug Administration

et al. 2016

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The depletion times of enrofloxacin and its metabolite ciprofloxacin as well as sulfaquinoxaline and oxytetracycline were evaluated in broiler chickens that had been subjected to pharmacological treatment. The presence and residue levels of these drugs in muscle tissue were evaluated using an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method that was validated in this work. The results showed the presence of all antimicrobial residues; however, the presence of residues at concentrations higher than the drugs’ maximum residue limit (MRL) of 100 μg kg-1 was found only during the treatment period for oxytetracycline and until two days after discontinuation of the medication for enrofloxacin, ciprofloxacin and sulfaquinoxaline. It was concluded that the residues of all antimicrobials were rapidly metabolized from the broiler muscles; after four days of withdrawal, the levels were lower than the limit of quantification (LOQ) of the method for the studied analytes.

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Section: Resultsmentioning

confidence: 59%

Evaluation of the Presence and Levels of Enrofloxacin, Ciprofloxacin, Sulfaquinoxaline and Oxytetracycline in Broiler Chickens after Drug Administration

et al. 2016

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“…Having said that consumers are advised to buy eggs that have been refrigerated, clean and not cracked before processing/cooking. Especially pregnant women, babies, older adults and people with weakened immune systems should use egg products with caution [51] [84] [88].…”

Section: Awareness To Ensure Food Safety Of Eggsmentioning

confidence: 99%

An Updated Review on Chicken Eggs: Production, Consumption, Management Aspects and Nutritional Benefits to Human Health

Zaheer¹

2015

FNS

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Ancestors of the modern chicken were domesticated from members of the Gallus genus probably 7 to 8 thousand years ago in southeastern Asia. Subsequently, they spread globally for meat and egg production. In the chicken egg, there is a balance of numerous, high-quality nutrients, many of which are highly bioavailable. The egg confers a multitude of health benefits to consumers emphasizing its classification as a functional food. Current global per capita egg consumption estimates approach 9 kg annually but vary greatly on a regional basis. This review deals with global production, consumption, and management aspects such as hygiene, feeding, and housing. Management aspects play key roles in the composition, quality, food safety, and visual (consumer) appeal of the egg. Also the manipulation of egg nutrients and value for human health is discussed.

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“…Largescale production is associated with great responsibility and the need for best practices to maintain meat quality. The grouping of a large number of animals in a small space is a factor which facilitates the rapid spread of bacterial infections in farm environments (5,21,22). Despite the use of various treatment protocols designed to improve animal welfare and the animals' subsequent resistance, antimicrobial substances ultimately remain the most effective for mitigating the losses caused by infections (21).…”

Section: Introductionmentioning

confidence: 99%

“…It offers low solution preparation cost, easy distribution and storage, fast administration to all birds in the early stages of disease, and quick dose or drug change (22). However, this method of administration has a few disadvantages which are associated with water quality (requiring it to be pure and have neutral pH and suitable hardness level), water hygiene (in that it must be clean, disinfected, and descaled), and the physicochemical properties of drugs (their solubility in water, adsorption in the solid phase, and formation of complexes with ions present in drinking water).…”

Section: Introductionmentioning

confidence: 99%

Effect of doxycycline concentrations in chicken tissues as a consequence of permanent exposure to enrofloxacin traces in drinking water

Gbylik-Sikorska

Posyniak

Śniegocki

et al. 2016

Journal of Veterinary Research

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Introduction: The main problem in poultry farming is the difficulty in producing food of animal origin without using antibacterial agents. Because most antibacterial compounds are dispensed in water, some water supply systems can be contaminated by antibiotics which are then administered to the animals unintentionally. This can lead to unexpected increases in antibiotic residues in food of animal origin. The aim of the present study was to determine whether the constant exposure of chicken broilers to enrofloxacin affects the withdrawal time of a therapeutic doxycycline that is intentionally administered to the chickens. Material and Methods: The concentrations of doxycycline, enrofloxacin, and ciprofloxacin were determined by LC-MS/MS in muscles and liver of the chickens. Results: Doxycycline residue concentrations in the chicken tissues from the group that received trace amounts of enrofloxacin were nearly 50% greater than those of the group that received only doxycycline. Conclusion: These results indicated that constant exposure to enrofloxacin in trace amounts significantly influences the residual doxycycline concentration in chicken tissues.

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The use of antimicrobial agents in broiler chickens

Cited by 104 publications

References 51 publications

Evaluation of the Presence and Levels of Enrofloxacin, Ciprofloxacin, Sulfaquinoxaline and Oxytetracycline in Broiler Chickens after Drug Administration

Evaluation of the Presence and Levels of Enrofloxacin, Ciprofloxacin, Sulfaquinoxaline and Oxytetracycline in Broiler Chickens after Drug Administration

An Updated Review on Chicken Eggs: Production, Consumption, Management Aspects and Nutritional Benefits to Human Health

Effect of doxycycline concentrations in chicken tissues as a consequence of permanent exposure to enrofloxacin traces in drinking water

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