The use of autogenous tooth bone graft is an efficient method of alveolar ridge preservation – meta-analysis and systematic review

Abstract

Background Ridge resorption following tooth extraction may be reduced by alveolar ridge preservation (ARP). Previous randomized clinical trials and systematic reviews have suggested that autogenous tooth bone graft (ATB) can be an effective alternative material for ARP. However, the results are heterogeneous. Therefore, our research aimed to evaluate the efficacy of ATB in ARP. Methods A systematic search was conducted in Cochrane Library, Embase, MEDLINE and Scopus for studies published from inception to 31 November 2021. We searched searched for randomized, non-randomized controlled trials and case series reporting on ATB use for ARP. The primary outcome was the ridge width difference pre- and post-surgery, measured in millimetres (mm) measured on CBCT (cone beam computed tomography). The secondary outcomes were the histological results. We followed the PRISMA2020 recommendations for reporting our systematic review and meta-analysis. Results The analysis included eight studies for the primary and six for the secondary outcomes. The meta-analysis revealed a positive ridge preservation effect with a pooled mean difference ridge width change of -0.72 mm. The pooled mean residual graft proportion was 11.61%, and the newly formed bone proportion was 40.23%. The pooled mean of newly formed bone proportion was higher in the group where ATB originated from both the root and crown of the tooth. Conclusions ATB is an effective particulate graft material in ARP. Complete demineralization of the ATB tends to decrease the proportion of newly formed bone. ATB can be an attractive option for ARP. Trial registration The study protocol was registered on PROSPERO (CRD42021287890).

Alveolar ridge preservation in sockets with severe periodontal destruction using autogenous partially demineralized dentin matrix: A randomized controlled clinical trial

“…reported 43 . This result was similar to a systemic review that showed the mean newly formed bone proportion of the autogenous tooth bone graft was 40%, and the residual graft proportion was 12% 44 …”

Using autogenous tooth sticky bone graft repair mandibular third molar dentigerous cyst osseous defects

“…The limitations of this investigation and the grafting material itself should be acknowledged. “Demand exceeding supply” is the primary sore point in autogenous tooth bone grafting [ 9 – 11 , 13 , 19 – 21 ]. In this investigation, this issue was also encountered.…”

“…However, its “rob Peter to pay Paul” supplying patterns resulted in high bone resorption and complex donor site postoperative complications [ 8 ]. There is accumulating evidence for using autogenous teeth as a grafting material for alveolar bone restoration, socket preservation, and maxillary sinus lifting, and this method shows excellent osteoconductivity, osteoinductivity and osteogenicity [ 9 , 10 ]. There have been no studies that have described the repair of bone defects of dentigerous cysts arising from mandibular third molar grafts prepared with autogenous tooth graft material [ 11 ].…”

Efficacy of Autogenous Dentin Biomaterial on Alveolar Ridge Preservation: A Randomized Controlled Clinical Trial

“…Based on the systematic review findings, the ADB can be an alternative, cost-effective, and sustainable biomaterial for alveolar ridge preservation [21]. Different graft materials are currently available for alveolar ridge preservation.…”

“…Furthermore, establishing a standardized point for the CBCT linear measurements is mandatory for accurate assessments. This study is aimed at evaluating the role of autogenous dentine biomaterials in preserving the alveolar ridge after extraction of a single retained root in the maxillary nonmolar sites by clinical, tomographical, and histological examinations with a surgical stent as a reference point [ 21 ]. We hypothesized a difference between spontaneous healing and preserved extraction sockets, while the null hypothesis is that there is no significant difference between spontaneous healing and preserved extraction sockets with ADB in terms of dimensional changes and healing characteristics.…”