The study of the efficiency of Serenade ASO, SC biological preparation applied 5 times in a dose of 6 l/ha and 8 l//ha against grey rot of summer raspberry at different levels of the disease development for 2020–2021 showed its high biological (51,8–63,3 %) and economic (from 1,5 dt/ha to 12,0 dt/ha of the saved yield) efficiency.