The Use of Blood Components in Tissue Engineering

Egorihina, Marpha N

doi:10.20333/2500136-2018-3-14-23

SMR

2018

DOI: 10.20333/2500136-2018-3-14-23

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The Use of Blood Components in Tissue Engineering

Marpha N Egorihina¹

Abstract: Приволжский федеральный медицинский исследовательский центр, Нижний Новгород 603115, Российская Федерация Резюме. Обзор показывает состояние научных исследований в области использования наиболее востребованных с точки зрения тканевой инженерии и регенеративной медицины компонентов крови в качестве материалов для создания скаффолдов. Проанализированы данные исследований структуры и свойств скаффолдов, активности клеточных процессов, проангиогенного потенциала клеточных матриц обусловленные свойствами различных … Show more

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Cited by 2 publications

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Platelet-rich plasma products in traumatology and orthopaedics: classification issues (literature review)

Котельников

Петрович²,

Dolgushkin

et al. 2020

Aspirantskiy Vestnik Povolzhiya

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In recent years, biological growth factors contained in platelet-rich plasma (PRP) obtained from the whole blood have been actively used to regenerate tissues of the musculoskeletal system. There are a lot of methods for preparing PRP, devices and modes for obtaining it, including ready-made services for use in traumatology and orthopedics. A number of well-known protocols miss important points and features of handling biological material, and fail to give clear characteristics of the resulting product. At the same time, there are a number of products that are completely opposite in composition, method, place of application and time of application, which the authors denote as PRP. In the domestic and foreign literature, several attempts have been made to characterize and classify the types of products containing plasma with platelets as a basis. In this article, we describe the existing systems used to classify PRP drugs, highlight their advantages and disadvantages. Of course, due to the active use of PRP in various fields of medicine, there remains a need for the standardized universal nomenclature for describing biological therapies, as well as for a comprehensive and reproducible classification system for products obtained from autologous blood.

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Platelet-rich plasma products in traumatology and orthopaedics: classification issues (literature review)

Котельников

Петрович²,

Dolgushkin

et al. 2020

Aspirantskiy Vestnik Povolzhiya

View full text Add to dashboard Cite

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Application of autoplasma enriched with thrombocytes in the comprehensive treatment of acute pancreatitis

Mikhailov,

Khalimov,

Remnyakov

2024

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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The OBJECTIVE was to assess the proposed treatment method for patients with acute pancreatitis in the 1 A phase of the disease’s development.METHODS AND MATERIALS. The data from the treatment of patients in the surgical departments of the City Clinical Hospital ¹ 6 in Izhevsk (Clinic of the Department of General Surgery, Izhevsk State Medical Academy) were ana lyzed. Two groups of patients with acute pancreatitis in the 1A phase of the disease development were formed. In the observation group, in addition to the basic treatment, autoplasmic thrombocyte concentrate was administered into the round ligament of the liver. The dynamics of the process and treatment outcomes were assessed based on the criteria scale of primary express assessment of acute pancreatitis severity by the St. Petersburg Research Institute named after I. I. Dzhanelidze (2006), leukocyte index of intoxication by V. K. Ostrovsky (2018), and the J. Ranson scale (1974).RESULTS. The use of autoplasmic thrombocyte concentrate in the observation group allows reducing the number of minimally invasive interventions to 17.7 %, or by 42.1 %, and the number of laparotomies to 5, or by 54.5 %, compared to the comparison group, avoiding fatal outcomes.CONCLUSION. The use of autoplasmic thrombocyte concentrate in the comprehensive treatment of patients with acute pancreatitis in the 1 A phase of development and its targeted delivery through the round ligament of the liver allows preventing lethality, reducing the number of complications of acute pancreatitis requiring surgical intervention.

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The Use of Blood Components in Tissue Engineering

Cited by 2 publications

References 40 publications

Platelet-rich plasma products in traumatology and orthopaedics: classification issues (literature review)

Platelet-rich plasma products in traumatology and orthopaedics: classification issues (literature review)

Application of autoplasma enriched with thrombocytes in the comprehensive treatment of acute pancreatitis

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