Tattoos are not a symptom of a mental disturbance. Most of the tattooed have simple motives and explanations: 'because I like it', 'because I'm a tomboy', 'to remember'. They do not accept the interpretations that the researchers describe and impose. Actually, the act of tattooing is more sacred to the subjected than the tattoo itself. (Kazandjieva and Tsankov [1]) Tattoos are becoming increasingly common in all demographic groups globally and consequently so are clinician encounters with tattooed individuals. Tattoos have the potential to have an impact on clinicianpatient interaction, ultimately affecting clinical decision-making and patient outcomes. Tattoos may affect the clinician's first impression of the patient, their physical and psychological assessment, and thus their management of that patient. [2] Furthermore, tattoos and their complications are often the primary reason for seeking medical help. Considering the high prevalence of tattoos, many clinicians do not have sufficient knowledge of tattoos and tattooing to make informed clinical decisions. In this brief review, we provide practising clinicians with basic knowledge regarding tattoos to enable them to forge more functional clinician-patient relationships and to guide them in their daily practice. What is a tattoo? A tattoo refers to implantation of an exogenous pigment into the skin or mucous membranes. Types of tattoos Tattoos can be accidental or deliberate, permanent or temporary, professional or amateur, cosmetic, decorative or medical. Accidental tattoos are also referred to as traumatic tattoos, and result from inoculation into a wound of substances such as asphalt, amalgam, graphite, ink or gun powder. Permanent tattoos involve a colourfast pigment implanted below the dermo-epidermal junction and retained by macrophages and fibroblasts in the dermis. Temporary tattoos resemble a permanent tattoo, but are painted or airbrushed or are a decal on the surface of the skin and usually last for a few days. Professional tattoos are created by trained individuals at a tattoo parlour, usually with a tattoo machine. The pigment is mostly evenly dispersed in the dermis. Amateur tattoos are often applied at home, using only a needle and one colour ink. Ink deposition tends to be more superficial and variable. Cosmetic tattoos involve the use of pigment to enhance the appearance of body parts, resemble make-up or mask deformities. These include permanent make-up, tattoos over surgical scars and nipple tattoos after a mastectomy. Medical tattoos are used to treat a medical condition, communicate medical information, or mark a body location for medical procedures or future review. Invisible tattoos are also called UV or black-light tattoos and are made with dyes that fluoresce and glow visibly under ultraviolet light. History, evolution and epidemiology of tattoos Tattoos are as old as recorded human history, dating back >5 000 years. Ötzi the Iceman, whose 5 300-year-old freeze-dried body was discovered in the Tyrolean Alps in 1991, was tattooed over h...