The Use of Bupivacaine in Elective Inguinal Herniorrhaphy as a Fast and Safe Technique for Relief of Postoperative Pain

Bays, Ronald A.; Barry, Laura A; Vasilenko, Peter

doi:10.1097/00132586-199208000-00049

Cited by 16 publications

(8 citation statements)

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“…Although minimally invasive surgery is characterized by reduced postoperative pain, it is not completely painless, [1,4]. Patients undergoing laparoscopic repair of inguinal hernia suffer a considerable amount of pain on the day of surgery, frequently requiring narcotic analgesics [1,4,7,8].…”

Section: Discussionmentioning

confidence: 99%

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Preperitoneal bupivacaine attenuates pain following laparoscopic inguinal hernia repair

et al. 2004

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Section: Discussionmentioning

confidence: 99%

“…Patients undergoing laparoscopic repair of inguinal hernia suffer a considerable amount of pain on the day of surgery, frequently requiring narcotic analgesics [1,4,7,8]. Early postoperative pain may decrease early ambulation and delay rapid discharge.…”

Section: Discussionmentioning

confidence: 99%

Preperitoneal bupivacaine attenuates pain following laparoscopic inguinal hernia repair

et al. 2004

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“…Because many centers are now using local anesthetics to relieve postoperative pain and to prolong analgesia, the results found in some of the studies regarding local anesthetics suggest that these agents should be avoided in poorly healing wounds, leg ulcers, or anywhere that fast healing is essential [5][6][7][8].…”

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confidence: 99%

Experimental Studies on the Effect of Lidocaine on Wound Healing

et al. 1998

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Local anesthetics have several effects on wound healing. In experimental studies, procaine at high concentrations has been proved to retard healing in surgical wounds by diminishing the synthesis of mucopolysaccharides and hence probably collagen. Other studies have shown that lidocaine and bupivacaine inhibit collagen synthesis in fibroblast tissue cultures in rats. This study was designed to evaluate the effect of lidocaine on wound healing. An experimental, prospective, comparative, crossover and double-blind study was designed. Forty male guinea pigs, weighing 300 to 600 g, were randomly assigned to two groups. In control group A (20 animals), skin and subcutaneous tissue in a clean wound were incised and infiltrated with regular saline solution; in group B 20 animals were infiltrated with 1% lidocaine. All animals were sacrificed on day 8 and evaluated for breaking strength, number of collagen fibers by morphometry, and histologic examination of collagenization, edema, vascularity, and presence of acute and chronic inflammatory cells. The histopathologic appearance of tissues infiltrated with lidocaine did not vary consistently in relation to collagenization, edema, or acute and chronic inflammatory processes. The mean breaking strength between both groups was not statistically significant (p = 0.120). Important statistical differences were observed in vascularity (p < 0.003) and morphometric results (p < 0.001), where collagen was found in small amounts in the lidocaine group. The results of this study suggest that local infiltration of lidocaine produces significant histopathologic changes, but it does not substantially alter wound healing as there were no differences in the breaking strength of the wounds.

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“…Bei unserer Studie wurde Bupivacain in Anlehnung an Untersuchungen von Alston [1], Bays [4] und Casey [5] verwendet. Bupivacain ist ein lokalwirkendes Analgetikum mit langer Wirkdauer (6 h ohne Adrenalin [14], bis zu 30 h mit Adrenalinzusatz).…”

Section: Diskussionunclassified

“…Unsere Ergebnisse zeigen, dab die alleinige intraoperative Nervenblockade durch die einmalige Gabe eines langwirkenden Lokalan/isthetikums in Kombination mit einem Vasokonstriktor den Leistenschmerz nach Herniotomie sowohl am Operationstag als auch an den folgenden Tagen, fiber die Wirkdauer des Analgetikums hinaus, deutlich senkt. Bays [4] beschreibt einen an~sthetisierenden Effekt ffir 12 h nach Spfilen der Wunde mit Bupivacain mit Adrenalin. In unseren Untersuchungen kann fiber die Zeitspanne bis zur ersten Schmerzmittelgabe aufgrund der unterschiedlichen Narkoseformen (Gasnarkosen, Mischnarkosen mit Opiaten und Leitungsan/isthesie) keine eindeutige Aussage ge-.…”

Section: Diskussionunclassified

Ein konzept zur senkung postoperativer schmerzen nach leistenhernienoperation

Röder

Weigel

Isemer

1994

Langenbecks Arch Chir

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In Germany approximately 150,000 inguinal hernias are surgically corrected every year. In addition to developing an optimum operation technique it is also the responsibility of a surgeon to treat pain during and after surgery. In a prospective random double-blind study, the pain after herniotomy performed with intraoperative anesthesia of the ilioinguinal and iliohypogastric nerves with a long-acting local anesthetic combined with a vasoconstrictor was compared by means of scores on a scale from 1 to 10 with pain in a control group. The results suggest that the intraoperative anesthesia reduces pain after surgery both on the day of the operation and afterwards, when the effect of the local anesthetic has decreased. An optimum pain therapy therefore has to start during surgery. Use of a local anesthetic is especially suitable. Side effects of systemic analgesics are avoided, and perioperative risks of ambulant hernia surgery can be reduced.

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The Use of Bupivacaine in Elective Inguinal Herniorrhaphy as a Fast and Safe Technique for Relief of Postoperative Pain

Cited by 16 publications

References 0 publications

Preperitoneal bupivacaine attenuates pain following laparoscopic inguinal hernia repair

Preperitoneal bupivacaine attenuates pain following laparoscopic inguinal hernia repair

Experimental Studies on the Effect of Lidocaine on Wound Healing

Ein konzept zur senkung postoperativer schmerzen nach leistenhernienoperation

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