The Use of Carbon Fiber-Reinforced Instrumentation in Patients with Spinal Oncologic Tumors: A Systematic Review of Literature and Future Directions

Perez-Roman, Roberto J.; Boddu, James; Bashti, Malek; Bryant, Jean-Paul; Amadasu, Efosa; Gyedu, Joseph S.; Wang, Michael Y.

doi:10.1016/j.wneu.2023.01.090

Cited by 7 publications

(5 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This modified plastic has excellent radiographic characteristics with no noted differences in outcomes or complications from traditional Ti or PEEK [73]. CFR-PEEK may enhance early detection of tumor recurrence and radiation dosing accuracy, though limited clinical data currently exist [74]. When PEEK is doped with Ti, it may show improved subsidence rates relative to PEEK alone.…”

Section: Peekmentioning

confidence: 99%

Emerging Technologies within Spine Surgery

Foley,

Hardacker,

McCarthy

2023

Life

View full text Add to dashboard Cite

New innovations within spine surgery continue to propel the field forward. These technologies improve surgeons’ understanding of their patients and allow them to optimize treatment planning both in the operating room and clinic. Additionally, changes in the implants and surgeon practice habits continue to evolve secondary to emerging biomaterials and device design. With ongoing advancements, patients can expect enhanced preoperative decision-making, improved patient outcomes, and better intraoperative execution. Additionally, these changes may decrease many of the most common complications following spine surgery in order to reduce morbidity, mortality, and the need for reoperation. This article reviews some of these technological advancements and how they are projected to impact the field. As the field continues to advance, it is vital that practitioners remain knowledgeable of these changes in order to provide the most effective treatment possible.

show abstract

Section: Peekmentioning

confidence: 99%

Emerging Technologies within Spine Surgery

Foley,

Hardacker,

McCarthy

2023

Life

View full text Add to dashboard Cite

show abstract

“…In radiation oncology treatment, CRF-PEEK devices are also advantageous due to their decreased imaging artifact during planning and decreased dose perturbation during RT delivery. For these reasons, the manufacturing processes for CRF-PEEK materials continue to evolve and improve, and orthopedic applications for them in the spine and the appendicular skeleton are increasing [8,9].…”

Section: Discussionmentioning

confidence: 99%

“…The use of CFR-PEEK instrumentation (rods and pedicle screws) for the treatment of primary and metastatic spinal tumors has been recently described in several clinical studies [9][10][11][12], and it has been demonstrated that postoperative CT and MRI scans show reduced artifacts in patients who received CFR-PEEK pedicle screws for the treatment of spinal tumors when compared with standard titanium alloy implants [13].…”

Section: Introductionmentioning

confidence: 99%

Carbon Fiber-Reinforced PolyEtherEtherKetone (CFR-PEEK) Instrumentation in Degenerative Disease of Lumbar Spine: A Pilot Study

Ghermandi

Tosini

Lorenzi³

et al. 2023

Bioengineering

View full text Add to dashboard Cite

CFR-PEEK is gaining popularity in spinal oncological applications due to its reduction of imaging artifacts and radiation scattering compared with titanium, which allows for better oncological follow-up and efficacy of radiotherapy. We evaluated the use of these materials for the treatment of lumbar degenerative diseases (DDs) and considered the biomechanical potential of the carbon fiber in relation to its modulus of elasticity being similar to that of bone. Twenty-eight patients with DDs were treated using CRF-PEEK instrumentation. The clinical and radiographic outcomes were collected at a 12-month FU. Spinal fusion was evaluated in the CT scans using Brantigan scores, while the clinical outcomes were evaluated using VAS, SF-12, and EQ-5D scores. Out of the patients evaluated at the 12-month FU, 89% showed complete or almost certain fusion (Brantigan score D and E) and presented a significant improvement in all clinical parameters; the patients also presented VAS scores ranging from 6.81 ± 2.01 to 0.85 ± 1.32, EQ-5D scores ranging from 53.4 ± 19.3 to 85.0 ± 13.7, SF-12 physical component scores (PCSs) ranging from 29.35 ± 7.04 to 51.36 ± 9.75, and SF-12 mental component scores (MCSs) ranging from 39.89 ± 11.70 to 53.24 ± 9.24. No mechanical complications related to the implant were detected, and the patients reported a better tolerance of the instrumentation compared with titanium. No other series of patients affected by DD that was stabilized using carbon fiber implants have been reported in the literature. The results of this pilot study indicate the efficacy and safety of these implants and support their use also for spinal degenerative diseases.

show abstract

“…In this setting, cement augmentation is one of the methods that have been studied in this population aiming at optimizing hardware stability and allowing for shorter constructs, ultimately working in synergy with an MIS tactic. This technique has demonstrated a twofold increase in screw pullout strength, 8,9 and a recent analysis 4 of short-segment cement-augmented constructs showed just one failure among 44 cases with an average follow-up of 10.7 months.…”

Section: Transcriptmentioning

confidence: 93%

“…Carbon fiber-reinforced PEEK hardware enables more accurate radiation planning and local control monitoring due to fewer artifact on imaging and reduced scattering effect on radiation. [8][9][10] Moreover, compared to titanium, it has a lower elastic modulus which ultimately leads to less stress at the bone-hardware interface. This may also be advantageous as poor bone quality is a prevalent issue among cancer patients.…”

Section: Transcriptmentioning

confidence: 99%

MIS technique for separation surgery in lumbar spine metastatic disease

Martins Coelho Junior,

Dhaliwal,

Chakravarthy

2024

Neurosurgical Focus: Video

View full text Add to dashboard Cite

Around 40% of cancer patients present with spinal metastases (SM), the lumbar spine being the second most involved site (15%–30%) after the thoracic (60%–80%). Since the development of separation surgery, minimally invasive surgery (MIS) has increasingly been applied to approach SM, mirroring benefits yielded in the degenerative realm. Moreover, preoperative embolization potentially enhances local control for certain radioresistant histologies. Carbon fiber–reinforced PEEK hardware reduces image artifact, facilitating more accurate follow-up and radiotherapeutic planning. Additionally, short-segment cement-augmented constructs may be beneficial to decrease surgical morbidity and operative risk in this population. The authors present a lumbar spinal metastasis treated with MIS techniques. The video can be found here: https://stream.cadmore.media/r10.3171/2024.1.FOCVID23222

show abstract

The Use of Carbon Fiber-Reinforced Instrumentation in Patients with Spinal Oncologic Tumors: A Systematic Review of Literature and Future Directions

Cited by 7 publications

References 29 publications

Emerging Technologies within Spine Surgery

Emerging Technologies within Spine Surgery

Carbon Fiber-Reinforced PolyEtherEtherKetone (CFR-PEEK) Instrumentation in Degenerative Disease of Lumbar Spine: A Pilot Study

MIS technique for separation surgery in lumbar spine metastatic disease

Contact Info

Product

Resources

About