1968
DOI: 10.1016/0020-708x(68)90023-9
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The use of Cerenkov radiation in the measurement of β-emitting radionuclides

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Cited by 83 publications
(37 citation statements)
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“…According to the mechanism of CR, as long as these positrons have a superluminal speed in a dielectric medium CR will be produced until interactions with the medium cause these particles to lose kinetic energy to the point that their speed, v, drops below the speed of light in that medium, v n . Thus, this threshold particle kinetic energy that is required for CR in a particular medium can also be derived by combining Equations 1 and 2, and in biologic tissue this threshold was calculated to be approximately 260 keV, which is significantly lower than 635 keV, the maximum kinetic energy of 18 F positrons (6,7).…”
Section: Physics Of Crmentioning
confidence: 99%
“…According to the mechanism of CR, as long as these positrons have a superluminal speed in a dielectric medium CR will be produced until interactions with the medium cause these particles to lose kinetic energy to the point that their speed, v, drops below the speed of light in that medium, v n . Thus, this threshold particle kinetic energy that is required for CR in a particular medium can also be derived by combining Equations 1 and 2, and in biologic tissue this threshold was calculated to be approximately 260 keV, which is significantly lower than 635 keV, the maximum kinetic energy of 18 F positrons (6,7).…”
Section: Physics Of Crmentioning
confidence: 99%
“…For example, taking the refractive index of water to be approximately 1.33, the speed of light in water is approximately 0.75 c. On the other hand, the velocity of the β particles emitted from radioactive substances is very near to the velocity of light (c). For 18 a medium is relative to the refractive index of the medium, this correlation was figured out by Mitchell et al [4]. We plotted the threshold energy of charged particles as a function of the refractive index of medium according to the Equation (1) ( Figure 1A).…”
Section: The History and Basic Theory And Features Of Crmentioning
confidence: 99%
“…In water, which has a refractive index of 1.33 in the visible spectrum, the threshold for the production of Cerenkov light for a b-particle is 0. positron-emitting radionuclides used in positron emission tomography (PET), have endpoint energies significantly higher than these thresholds and therefore produce detectable Cerenkov light in water or in tissue [8]. We note that Cerenkov light has previously been used quantitatively for in vitro applications [13,14] and more recently to monitor a microfluidics apparatus [15]. To estimate and understand the intensity of the light emission, we consider the various factors in equation (2.1).…”
Section: Cerenkov Radiation For Molecular Imaging: Theory and Simulatmentioning
confidence: 99%