“…Although, most adverse morbid outcomes in high-risk patients undergoing major abdominal surgery are not reduced by use of a combined epidural and general anesthesia technique, the improvement in analgesia and reduction in respiratory failure and the low risk of serious adverse events makes it likely that high-risk patients undergoing major intra-abdominal surgery will benefit from this combination technique [ 26 , 27 ]. Nevertheless, after the publication of the MASTER study, the use of this combination of techniques has declined in some parts of the world [ 28 ].…”