The Use of Fecal Calprotectin and Intestinal Ultrasound in the Evaluation and Management of Stricturing Crohn’s Disease in Pregnancy

Prentice, Ralley E; Wright, Emily K; Flanagan, Emma; Ross, Alyson L; Bell, Sally

doi:10.1093/ibd/izab214

“…The authors assessed the management of stricturing CD in two pregnant patients using FC levels and intestinal ultrasound, proving that FC can serve as a complementary tool to ultrasound findings in confirming therapeutic response. Moreover, an increased FC level during pregnancy is associated with later exacerbation and a higher risk of adverse fetal and maternal outcomes [109].…”

Section: Fecal Biomarkersmentioning

confidence: 99%

Current Approach to Risk Factors and Biomarkers of Intestinal Fibrosis in Inflammatory Bowel Disease

Dudek,

Talar-Wojnarowska

2024

Medicina

3

0

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Inflammatory bowel disease (IBD), especially Crohn’s disease (CD), characterized by a chronic inflammatory process and progressive intestinal tissue damage, leads to the unrestrained proliferation of mesenchymal cells and the development of bowel strictures. Complications induced by fibrosis are related to high rates of morbidity and mortality and lead to a substantial number of hospitalizations and surgical procedures, generating high healthcare costs. The development of easily obtained, reliable fibrogenesis biomarkers is essential to provide an important complementary tool to existing diagnostic and prognostic methods in IBD management, guiding decisions on the intensification of pharmacotherapy, proceeding to surgical methods of treatment and monitoring the efficacy of anti-fibrotic therapy in the future. The most promising potential markers of fibrosis include cartilage oligomeric matrix protein (COMP), hepatocyte growth factor activator (HGFA), and fibronectin isoform- extra domain A (ED-A), as well as antibodies against granulocyte macrophage colony-stimulating factor (GM-CSF Ab), cathelicidin (LL-37), or circulatory miRNAs: miR-19a-3p and miR-19b-3p. This review summarizes the role of genetic predisposition, and risk factors and serological markers potentially contributing to the pathophysiology of fibrotic strictures in the course of IBD.

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“…(Park et al, 2020), it stands out for being a low-cost, mobile, and, above all, non-ionizing medical imaging technology (Yuan et al, 2021). Because ultrasound is radiation-safe, it is the preferred imaging modality for children and pregnant women (Prentice et al, 2022) and has been widely used in the detection and severity assessment of COVID-19 for the same patient group (Allinovi et al, 2020). Lung infection due to COVID-19 can be seen and assessed in chest ultrasound images.…”

Section: Ultrasound In Covid-2019 Diagnosismentioning

confidence: 99%

Ultrasound-Based AI for COVID-19 Detection: A Comprehensive Review of Public and Private Lung Ultrasound Datasets and Studies

Morshed¹,

Shihab²,

Jahin³

et al. 2023

Preprint

0

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The COVID-19 pandemic has affected millions of people globally, with respiratory organs being strongly affected in individuals with comorbidities. Medical imaging-based diagnosis and prognosis have become increasingly popular in clinical settings to detect COVID-19 lung infections. Among various medical imaging modalities, ultrasound stands out as low-cost, mobile, and radiation-safe imaging technology. In this comprehensive review, we focus on ultrasound-based AI studies for COVID-19 detection that use public or private lung ultrasound datasets. We surveyed articles that used publicly available lung ultrasound datasets for COVID-19 and reviewed publicly available datasets and organize ultrasound-based AI studies per dataset. We analyzed and tabulated studies in several dimensions, such as data preprocessing, AI models, cross-validation, and evaluation criteria. In total, we reviewed 42 articles, where 28 articles used public datasets, and the rest used private data. Our findings suggest that ultrasound-based AI studies for the detection of COVID-19 have great potential for clinical use, especially for children and pregnant women. Our review also provides a useful summary for future researchers and clinicians who may be interested in the field.

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“…[8], it stands out for being a low-cost, mobile, and, above all, non-ionizing medical imaging technology [9]. Because ultrasound is radiation-safe, it is the preferred imaging modality for children and pregnant women [10] and has been widely used in the detection and severity assessment of COVID-19 for the same patient group [11]. Lung infection due to COVID-19 can be seen and assessed in chest ultrasound images.…”

Section: Ultrasound In Covid-2019 Diagnosismentioning

confidence: 99%

Ultrasound-Based AI for COVID-19 Detection: A Comprehensive Review of Public and Private Lung Ultrasound Datasets and Studies

Morshed¹,

Shihab²,

Jahin³

et al. 2023

Preprint

1

0

View full text Add to dashboard Cite

The COVID-19 pandemic has affected millions of people globally, with respiratory organs being strongly affected in individuals with comorbidities. Medical imaging-based diagnosis and prognosis have become increasingly popular in clinical settings to detect COVID-19 lung infections. Among various medical imaging modalities, ultrasound stands out as low-cost, mobile, and radiation-safe imaging technology. In this comprehensive review, we focus on ultrasound-based AI studies for COVID-19 detection that use public or private lung ultrasound datasets. We surveyed articles that used publicly available lung ultrasound datasets for COVID-19 and reviewed publicly available datasets and organize ultrasound-based AI studies per dataset. We analyzed and tabulated studies in several dimensions, such as data preprocessing, AI models, cross-validation, and evaluation criteria. In total, we reviewed 42 articles, where 28 articles used public datasets, and the rest used private data. Our findings suggest that ultrasound-based AI studies for the detection of COVID-19 have great potential for clinical use, especially for children and pregnant women. Our review also provides a useful summary for future researchers and clinicians who may be interested in the field.

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The Use of Fecal Calprotectin and Intestinal Ultrasound in the Evaluation and Management of Stricturing Crohn’s Disease in Pregnancy

Cited by 8 publications

References 10 publications

Current Approach to Risk Factors and Biomarkers of Intestinal Fibrosis in Inflammatory Bowel Disease

Current Approach to Risk Factors and Biomarkers of Intestinal Fibrosis in Inflammatory Bowel Disease

Ultrasound-Based AI for COVID-19 Detection: A Comprehensive Review of Public and Private Lung Ultrasound Datasets and Studies

Ultrasound-Based AI for COVID-19 Detection: A Comprehensive Review of Public and Private Lung Ultrasound Datasets and Studies

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