The use of fibroblasts in periodontology and implantology

Stepanova, І. І.

doi:10.1007/s10517-007-0275-8

Cited by 2 publications

(1 citation statement)

References 19 publications

(15 reference statements)

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“…TGF-α regulates angiogenesis, while TGF-β stimulates collagen I, fibronectin and osteonectin synthesis as well as bone matrix formation and basic fibroblast growth factor (bFGF). TGF-β is known to be expressed during the implantation process and contributes to implant osseointegration [104][105][106][107][108] . TGF-β has been also implicated in reparative dentinogenesis in the pulp 109 .…”

Section: Matrix Metalloproteinases (Mmps)mentioning

confidence: 99%

Osteoblast and Gingival Fibroblast Markers in Dental Implant Studies

Pivodová¹,

Franková²,

Ulrichová³

2011

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Section: Matrix Metalloproteinases (Mmps)mentioning

confidence: 99%

Osteoblast and Gingival Fibroblast Markers in Dental Implant Studies

Pivodová¹,

Franková²,

Ulrichová³

2011

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Periodontal Tissue Engineering and Regeneration: Current Approaches and Expanding Opportunities

Chen

Jin

2010

Tissue Engineering Part B: Reviews

304

254

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The management of periodontal tissue defects that result from periodontitis represents a medical and socioeconomic challenge. Concerted efforts have been and still are being made to accelerate and augment periodontal tissue and bone regeneration, including a range of regenerative surgical procedures, the development of a variety of grafting materials, and the use of recombinant growth factors. More recently, tissue-engineering strategies, including new cell- and/or matrix-based dimensions, are also being developed, analyzed, and employed for periodontal regenerative therapies. Tissue engineering in periodontology applies the principles of engineering and life sciences toward the development of biological techniques that can restore lost alveolar bone, periodontal ligament, and root cementum. It is based on an understanding of the role of periodontal formation and aims to grow new functional tissues rather than to build new replacements of periodontium. Although tissue engineering has merged to create more opportunities for predictable and optimal periodontal tissue regeneration, the technique and design for preclinical and clinical studies remain in their early stages. To date, the reconstruction of small- to moderate-sized periodontal bone defects using engineered cell-scaffold constructs is technically feasible, and some of the currently developed concepts may represent alternatives for certain ideal clinical scenarios. However, the predictable reconstruction of the normal structure and functionality of a tooth-supporting apparatus remains challenging. This review summarizes current regenerative procedures for periodontal healing and regeneration and explores their progress and difficulties in clinical practice, with particular emphasis placed upon current challenges and future possibilities associated with tissue-engineering strategies in periodontal regenerative medicine.

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The use of fibroblasts in periodontology and implantology

Cited by 2 publications

References 19 publications

Osteoblast and Gingival Fibroblast Markers in Dental Implant Studies

Osteoblast and Gingival Fibroblast Markers in Dental Implant Studies

Periodontal Tissue Engineering and Regeneration: Current Approaches and Expanding Opportunities

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