Background: The COVID-19 pandemic has exposed various clinical presentations, including respiratory, gastrointestinal, musculoskeletal and neurological symptoms. In this scenario, natural remedies have notably increased popularity due to their perceived therapeutic advantages. However, these remedies remain untested in terms of their effectiveness and role in mitigating COVID-19 symptoms. Aim: This study aims to examine how natural remedies can help manage COVID-19 symptoms and explore the complex relationship between symptomatology and consumption. Methods: An exploratory cross-sectional study with 215 Jordanians was conducted. A structured questionnaire was used to collect information about symptoms and natural remedies used by COVID-19 patients. Statistical analysis was conducted to identify relationships between symptoms and natural remedies used. Results: Natural remedies were used to treat mild symptoms (58.1%) and to help patients recover from their symptoms (40.5%). The use of natural remedies is associated with symptoms such as indigestion, coughing, shortness of breath, chest pain, nasal congestion, nausea, stomachache, diarrhoea and loss of smell. For headaches, 31.3% of participants used fenugreek, black seeds and sesame oil. Sore throats and coughs were treated with honey, turmeric, cinnamon, chamomile, lemon, olive oil, rosemary, sage, anise, sesame oil, parsley and cardamom. To treat nasal congestion, honey, garlic and anise were used. Severe loss of taste and smell were treated with onions and garlic. Each region offers unique natural remedies and preferences that reflect its distinct culture and environment. Conclusions: During the COVID-19 pandemic, natural remedies were found to be effective in treating upper respiratory infections among the adult Jordanian population. Individuals use natural remedies during health crises for a variety of purposes, emphasising the importance of a personalised approach.