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Introduction. In the complex therapy of acute bacterial sinusitis, drugs that have antibacterial, anti-inflammatory, mucolytic effects are widely used. The article discusses the effectiveness of the use of a phytopreparation containing standardized myrtol, limonene, cineol and alpha – pinene in the treatment of acute sinusitis in patients who have undergone SARS-CoV-2.Aim. To increase the effectiveness of conservative therapy of acute bacterial sinusitis in people who have undergone a new coronavirus infection (SARS-CoV-2) using a complex phytopreparation.Materials and methods. A simple randomized controlled clinical research study involved 83 patients suffering from acute bacterial sinusitis after a coronavirus infection. Potential, safety and recovery time were evaluated in two groups: a group of patients (n = 41) taking standardized Myrtol limonel, cineol and alpha – pinene (a phytotherapeutic drug), compared with a group (n = 42) taking an antibacterial drug. The severity of clinical manifestations was assessed according to the VAS scale, cognitive functions and memory were carried out using standard psychological tests and an assessment of the quality of life according to SNOT-22.Results and discussion. The use of Respero Myrtol forte, containing standardized Myrtol limonel, cineol and alpha-pinene, in the complex therapy of bacterial sinusitis in people who have undergone a new coronavirus infection (SARS-CoV-2) has significantly improved clinical symptoms, cognitive functions and the quality of life. Good drug tolerance, high potential and safety, recovery and improvement of the quality of life at an early date were noted.Conclusions. In the treatment of patients with bacterial sinusitis in people who have undergone a new coronavirus infection (SARS-CoV-2), Respiro Myrtol forte has shown high antibacterial, anti-inflammatory and mucolytic effects, good bioavailability, tolerance and safety.
Introduction. In the complex therapy of acute bacterial sinusitis, drugs that have antibacterial, anti-inflammatory, mucolytic effects are widely used. The article discusses the effectiveness of the use of a phytopreparation containing standardized myrtol, limonene, cineol and alpha – pinene in the treatment of acute sinusitis in patients who have undergone SARS-CoV-2.Aim. To increase the effectiveness of conservative therapy of acute bacterial sinusitis in people who have undergone a new coronavirus infection (SARS-CoV-2) using a complex phytopreparation.Materials and methods. A simple randomized controlled clinical research study involved 83 patients suffering from acute bacterial sinusitis after a coronavirus infection. Potential, safety and recovery time were evaluated in two groups: a group of patients (n = 41) taking standardized Myrtol limonel, cineol and alpha – pinene (a phytotherapeutic drug), compared with a group (n = 42) taking an antibacterial drug. The severity of clinical manifestations was assessed according to the VAS scale, cognitive functions and memory were carried out using standard psychological tests and an assessment of the quality of life according to SNOT-22.Results and discussion. The use of Respero Myrtol forte, containing standardized Myrtol limonel, cineol and alpha-pinene, in the complex therapy of bacterial sinusitis in people who have undergone a new coronavirus infection (SARS-CoV-2) has significantly improved clinical symptoms, cognitive functions and the quality of life. Good drug tolerance, high potential and safety, recovery and improvement of the quality of life at an early date were noted.Conclusions. In the treatment of patients with bacterial sinusitis in people who have undergone a new coronavirus infection (SARS-CoV-2), Respiro Myrtol forte has shown high antibacterial, anti-inflammatory and mucolytic effects, good bioavailability, tolerance and safety.
One of the urgent tasks of the Ministry of Health of the Russian Federation, noted in the State report on the state of sanitary and epidemiological welfare of the population, is the improvement and implementation of diagnostic and treatment and prevention technologies. First of all, this concerns the continued growth of respiratory viral infections, seasonal influenza epidemics, where SARS-CoV-2 coronavirus infection occupies a special place, which often cause various otorhinolaryngological complications – acute and exacerbations of chronic tonsillopharyngitis, rhinosinusitis, tubotitis, purulent otitis media. In the treatment of bacterial sinusitis, in accordance with clinical recommendations, intranasal corticosteroids, elimination therapy, herbal remedies, and antibacterial drugs are used. Due to the period of the SARS-CoV-2 pandemic, a significant proportion of patients took large doses of antibacterial drugs, which caused an increase in the resistance of microorganisms to them. In this regard, it is possible to use immunostimulating drugs that stimulate cellular and humoral immunity, promote the development of a specific immune response and activate nonspecific defense factors such as lysozyme, mucin, lactoferrin and normalize mucociliary clearance. As a rule, the identification of a viral agent is carried out in case of a severe clinical course of the disease or complications from the ORL and other organs, and the use of immunostimulating agents in complex therapy is necessary at the earliest possible time of the disease. In this context, the use of immunostimulants containing polyvalent antigenic complexes, including bacterial lysates, the most common pathogens of respiratory infections, is justified. It is preferable in these cases to use lysates of bacteria obtained by mechanical destruction of bacterial cells, since they have a more pronounced non-specific immunostimulatory and specific vaccinating effect.
Introduction. Acute respiratory viral infections are the most widespread diseases, accounting for up to 90% of all infectious pathology, which supports the relevance of optimizing the treatment of acute viral rhinosinusitis.Aim. Evaluate the dynamics of clinical symptoms of acute viral rhinosinusitis, which arose as part of an acute respiratory infection, when supplementing therapy with the drug Respero Myrtol (Pol-Boskamp GmbH and Co.KG, Germany), the active ingredient of which is myrtol standardized 120 mg in 1 capsule.Materials and methods. The dynamics of clinical symptoms of 20 cases of acute viral rhinosinusitis in comparison groups was analyzed. Traditional treatment of patients included taking propionic acid derivatives, ascorbic acid, intranasal use of decongestants and irrigation of the nasal cavity with isotonic saline solutions. Patients who have received traditional treatment are defined as a “standard therapy group”. To assess the effectiveness of therapy using standardized myrtol, 20 cases of acute viral rhinosinusitis against the background of acute respiratory viral infections with a similar severity were analyzed, in which patients received outpatient therapy with Respero Myrtol 2 capsules 3 times a day for 7 days in addition to the above treatment (the “myrtol therapy” group). The dynamics of the disease assessed: the number of days of disability before recovery, the period of normalization of body temperature in feverish patients, the need for vasoconstrictive intranasal agents after the seventh day of therapy, the period of complete relief of pain syndrome, the period of normalization of night sleep, the number of cases of bacterial superinfection and the need for systemic antibacterial therapy.The results. In the observed patients, the quality of sleep was restored faster, the pain syndrome was stopped earlier, less often there was a need for systemic antibiotics and prolonged use of intranasal decongestants. The disease proceeded with fewer days of disability.Conclusion. The study results have been shown to report the clinical efficacy of Respero Myrtol essential oils in the outpatient treatment of patients with acute rhinosinusitis.
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