The use of hormonal therapy in pediatric heart disease

Abstract

Introduction 3. The effects of tri-iodothyronine in the pediatric post-operative cardiac patients 3.1. Introduction 3.2. Regulation of thyroid hormone secretion and the mechanism of action 3.3. Changes to thyroid hormone metabolism following cardiac surgery 3.4. Trials of thyroid hormone supplementation in post-operative cardiac patients 4. Fludrocortisone treatment for syncope 4.1. Introduction 4.1. The mechanism of action of fludrocortisone 4.2. Treatment for syncope 5. Corticosteroids after cardiopulmonary bypass 5.1. Introduction 5.2. The mechanism of anti-inflammatory action of corticosteroids 5.3. Peri-operative steroid administration 5.4. Post-operative steroid administration 6. Arginine-vasopressin in shock 5.1. Introduction 5.2. Regulation of arginine-vasopressin secretion and the mechanism of action 5.3. Therapeutic use of arginine-vasopressin in shock 7. The effect of growth hormone on cardiac function 6.1. Introduction 6.2. Regulation of growth hormone secretion and the mechanism of action 6.3. GH treatment of cardiac dysfunction in GH deficiency 6.4. GH treatment of heart failure due to dilated cardiomyopathy 8. Summary and perspective 9. References 3. THE EFFECTS OF TRI-IODOTHYRONINE IN THE PEDIATRIC POST-OPERATIVE CARDIAC PATIENTS 3.1. Introduction Thyroid hormone is crucial to the growth, maturation, oxygen consumption, nerve function, and metabolism at all stages of human development. Of all organ systems that thyroid hormone affects, the heart is one

Point of care with serial N-terminal pro-B-type natriuretic peptide (NT-proBNP) for heart failure in patients with acute decompensation. An invited commentary

“…Consequently, there is an abnormality of peptides, ions, and excitation-contraction coupling. There is an alteration in calcium ions' delivery to the contractile sites with consequent impaired cardiac performance [ 8 ]. B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are peptides produced in small amounts in the heart.…”