The use of hyaluronic acid hydrogel as a tumour bed marker in breast-conserving therapy

Wiercińska, Judyta; Winiecki, Janusz; Wronczewska, Anna; Lebioda, Andrzej; Pławski, Krzysztof; Rhone, Piotr; Makarewicz, Roman

doi:10.1016/j.radonc.2020.07.041

Cited by 9 publications

(4 citation statements)

References 46 publications

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“…The use of iodinated PEG injected into the surgical cavity has been shown to improve the interobserver agreement in breast radiotherapy target definition, however there were issues with dilution due to seroma formation [23] . HA gels have been used as spacers in radiotherapy [22] and have recently been studied as a tumour bed marker in BCS [24] . Both these studies showed that interobserver variability in delineation increased with the use of injected gels.…”

Section: Discussionmentioning

confidence: 99%

Comparison of visibility of iodinated hydrogel and gadolinium-modified hyaluronic acid spacer gels on computed tomography and onboard imaging

Riberdy

Ruiz

Hoekstra

et al. 2022

Physics and Imaging in Radiation Oncology

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Section: Discussionmentioning

confidence: 99%

Comparison of visibility of iodinated hydrogel and gadolinium-modified hyaluronic acid spacer gels on computed tomography and onboard imaging

Riberdy

Ruiz

Hoekstra

et al. 2022

Physics and Imaging in Radiation Oncology

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“…It was described that HA conjugates comprised anticancer medicines containing sodium butyrate which showed enriched targeting capability toward cancer and advanced therapeutic efficiency linked to free-anticancer drugs dependent on the amount of exchange of HA with drugs. It is well known that cisplatin (cis-diaminedichloroplatinum or CDDP) is a widely engaged chemotherapeutic mediator for the cure of a widespread spectrum of solid cancer ( Wiercińska et al, 2020 ). Cho et al explained fruitful drainage of HA–cisplatin (HA–Pt) conjugates into the auxiliary lymph lumps with condensed systemic toxicities after being confined in osculation in a woman suffering from breast cancer.…”

Section: Recent Hyaluronic Acid Applications In the Biomedical Fieldmentioning

confidence: 99%

Advances in Hyaluronic Acid for Biomedical Applications

Yasin

Ren

et al. 2022

Front. Bioeng. Biotechnol.

112

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Hyaluronic acid (HA) is a large non-sulfated glycosaminoglycan that is the main component of the extracellular matrix (ECM). Because of its strong and diversified functions applied in broad fields, HA has been widely studied and reported previously. The molecular properties of HA and its derivatives, including a wide range of molecular weights but distinct effects on cells, moisture retention and anti-aging, and CD44 targeting, promised its role as a popular participant in tissue engineering, wound healing, cancer treatment, ophthalmology, and cosmetics. In recent years, HA and its derivatives have played an increasingly important role in the aforementioned biomedical fields in the formulation of coatings, nanoparticles, and hydrogels. This article highlights recent efforts in converting HA to smart formulation, such as multifunctional coatings, targeted nanoparticles, or injectable hydrogels, which are used in advanced biomedical application.

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“…In addition, HA is widely used due to its remarkable biocompatibility and biodegradability. The degradation time under natural conditions is about 6–12 months [35] . Therefore, HA is used by researchers as a raw material for hydrogel synthesis.…”

Section: The Hydrogels With Different Skeletonsmentioning

confidence: 99%

“…The degradation time under natural condi-tions is about 6-12 months. [35] Therefore, HA is used by researchers as a raw material for hydrogel synthesis.…”

Section: Hyaluronic Acid-based Hydrogelsmentioning

confidence: 99%

Application of Hydrogels as Carrier in Tumor Therapy: A Review

Zhang

Wang

Xia

et al. 2022

Chemistry An Asian Journal

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Cancer is one of the most intractable diseases in the world because of its high recurrence rate, high metastasis rate and high lethality rate. Traditional chemotherapy, radiotherapy and surgery have unsatisfactory therapeutic effects and cause many severe side effects at the same time. Hydrogel is a new type of biomaterial with the advantages of good biocompatibility and easy degradation, which can be used as a carrier of functional nanomaterials for tumor therapy. Herein, we represent the progress of hydrogels with different skeletons and their application as carrier in tumor treatment. The hydrogels are listed as polyethylene glycolbased hydrogels, chitosan-based hydrogels, peptide-based hydrogels, hyaluronic acid-based hydrogels, steroid-based hydrogels and other hydrogels by skeletons, and their properties, modifications and toxicities were introduced. Some representative applications of combined hydrogels with nanomaterial for chemotherapy, photodynamic therapy, photothermal therapy, sonodynamic therapy, chemodynamic therapy and synergistic therapy are highlighted.

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The use of hyaluronic acid hydrogel as a tumour bed marker in breast-conserving therapy

Cited by 9 publications

References 46 publications

Comparison of visibility of iodinated hydrogel and gadolinium-modified hyaluronic acid spacer gels on computed tomography and onboard imaging

Comparison of visibility of iodinated hydrogel and gadolinium-modified hyaluronic acid spacer gels on computed tomography and onboard imaging

Advances in Hyaluronic Acid for Biomedical Applications

Application of Hydrogels as Carrier in Tumor Therapy: A Review

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