Although hypnosis has been used clinically for years, research in this field is in its infancy. Authorities disagree on what distinguishes hypnotic from nonhypnotic therapy and on the circumstances under which an induction may add leverage to cognitive-behavioral treatments, Recent experimental evidence on the hypnotic treatment of obesity, cigarette smoking, alcoholism, clinical pain, warts, and asthma is reviewed. It is concluded that although hypnosis may be effective with addictive behavior, the therapeutic success is attributable to nonhypnotic factors. In contrast, hypnosis appears to be of unique value in the treatment of clinical pain, warts, and asthma. Differential effectiveness may be attributable to the nature of the disorders or to the manner in which hypnosis is used in treating them. The relevance of hypnotizability to treatment is discussed, as is the need to distinguish between genuine and placebo-based hypnotic effects. Future research must be more attentive to (a) the nature of the disorders and patient populations, (b) the adequate implementation of therapeutic techniques, (c) the context in which treatment is delivered, and (d) the influence of hypnotic susceptibility and other subject factors on outcome.