The Use of Imaging Studies in the Diagnosis and Management of Thyroid Cancer and Hyperparathyroidism

James, Charles A.; Starks, Michael Richard; MacGillivray, Dougald C.; White, Jonathan A.

doi:10.1016/s1055-3207(18)30230-8

Cited by 28 publications

(9 citation statements)

References 72 publications

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“…Ultrasound provides general information about the location of the lesion and its structure [9] ; whereas, 99mTc-sestamibi scanning can reveal abnormal and ectopic parathyroid tissue in the neck and elsewhere [10,11] . In cases where malignancy is suspected, higher-resolution anatomical studies are of considerable value [12] .…”

Section: Case Reportmentioning

confidence: 99%

FDG-PET/CT and parathyroid carcinoma: Review of literature and illustrative case series

Evangelista

Sorgato²,

Torresan³

et al. 2011

WJCO

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Parathyroid cancer is an uncommon malignant cancer and is associated with a poor prognosis. The staging of parathyroid cancer represents an important issue both at initial diagnosis and after surgery and medical treatment. The role of positron emission tomography/ computed tomography (PET/CT) with 18F-Fluorodeoxyglucose (18F-FDG) as an imaging tool in parathyroid cancer is not clearly reported in the literature, although its impact in other cancers is well-defined. The aim of the following illustrative clinical cases is to highlight the impact of PET/CT in the management of different phases of parathyroid cancer. We describe five patients with parathyroid malignant lesions, who underwent FDG PET/CT at initial staging, restaging and post-surgery evaluation. In each patient we report the value of PET/ CT comparing its findings with other common imaging modalities (e.g., CT, planar scintigraphy with 99mTc-sestamibi, magnetic resonance imaging) thus determining the complementary benefit of FDG PET/CT in parathyroid carcinoma. We hope to provide an insight into the potential role of PET/CT in assessing the extent of disease and response to treatment which are the general principles used to correctly evaluate disease status.

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Section: Case Reportmentioning

confidence: 99%

FDG-PET/CT and parathyroid carcinoma: Review of literature and illustrative case series

Evangelista

Sorgato²,

Torresan³

et al. 2011

WJCO

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“…The discovery of metastatic foci, even if no 131 I uptake is present, is useful, as it may lead to further treatment such as surgery or external radiotherapy. In such cases imaging modalities, such as high-resolution ultrasonography, computerized tomography scanning, or magnetic resonance imaging [4, 5], can be used as well as positron emission tomography with [ 18 F]fluorodeoxyglucose [6, 7, 8]which, however, is available only in some specialized centres.…”

Section: Discussionmentioning

confidence: 99%

“…However, there are patients who have elevated thyroglobulin levels and a negative 131 I TBS [2]. The use of modalities, such as high-resolution ultrasonography, computerized tomography, and magnetic resonance imaging, may be helpful in the presentation of residual disease in patients having a differentiated thyroid carcinoma [3, 4, 5], especially if focused on a specific organ or area of the body indicated by previous scintigraphic procedures. Positron emission tomography with [ 18 F]fluorodeoxyglucose has been used successfully for that purpose [6, 7, 8], being, however, available only in specialized centres.…”

Section: Introductionmentioning

confidence: 99%

Scintigraphy with [<sup>111</sup>In]Octreotide and <sup>201</sup>Tl in a Hürthle Cell Thyroid Carcinoma without Detectable Radio-Iodine Uptake

Kostoglou-Athanassiou¹,

Pappas²,

Gogou³

et al. 2003

Horm Res Paediatr

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Aim: To describe the visualization of recurrent disease by [¹¹¹In]octreotide and ²⁰¹Tl scintigraphy in a patient with Hürthle cell thyroid carcinoma, increased thyroglobulin levels, and a negative radio-iodine total-body scan. Methods: Scintigraphy with [¹¹¹In]octreotide and ²⁰¹Tl was performed, and a local recurrence in the thyroid bed was detected which was excised by surgery. Results: On histology, the tumour proved to be a Hürthle cell carcinoma, and within the tumour somatostatin receptors were detected by RT-PCR. Conclusion: Scintigraphy with [¹¹¹In]octreotide and ²⁰¹Tl is an alternative imaging method for the detection of residual disease in patients with a differentiated thyroid carcinoma having increased thyroglobulin levels and a negative radio-iodine total-body scan.

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“…Ultrasound is fast, non-invasive and useful for detecting cervical recurrence (17,18). CT and MRI are especially useful for detecting mediastinal and thoracic parathyroid cancer (17).…”

Section: Diagnosismentioning

confidence: 99%

“…Radioisotope imaging, in the form of 201 Th, 99m Tc and, more recently, sestamibi, has frequently been used to localize abnormal parathyroid tissue (18). Sestamibi is concentrated in the mitochondria, which are abundant in the parathyroid, making it a useful isotope for imaging abnormal parathyroi d tissue (18).…”

Section: Diagnosismentioning

confidence: 99%

Management of Cancer of the Parathyroid

Rao

Shaha

Singh

et al. 2002

Acta Oto-Laryngologica

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The Use of Imaging Studies in the Diagnosis and Management of Thyroid Cancer and Hyperparathyroidism

Cited by 28 publications

References 72 publications

FDG-PET/CT and parathyroid carcinoma: Review of literature and illustrative case series

FDG-PET/CT and parathyroid carcinoma: Review of literature and illustrative case series

Scintigraphy with [<sup>111</sup>In]Octreotide and <sup>201</sup>Tl in a Hürthle Cell Thyroid Carcinoma without Detectable Radio-Iodine Uptake

Management of Cancer of the Parathyroid

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