The use of integrative medical services to address psychological concerns around infertility in an Indian academic medical centre

Nayak, Hita; Gerstl, Brigitte; Sharma, Neha; Appaneravanda, Lohith Chengappa; Gunasheela, Devika

doi:10.4103/jhrs.jhrs_188_21

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…However, it is still unclear that whether psychological burden could affect CRC survivors' gut microbiome distribution and how to modulate. Aimed to care cancer patients' well-being as whole person, integrative medicine has been used more and more for psychological supports for cancer survivors in many countries [18,19]. Existing studies have revealed that mindfulness meditation, yoga, and other mind-body therapies were found to be helpful on psychosomatic symptom management for both CRC and other cancer survivors [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Effect of traditional Chinese medicine combined group psychotherapy on psychological distress management and gut micro-biome regulation for colorectal cancer survivors: a single-arm phase I clinical trial

Sun,

Pang,

Wang

et al. 2023

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Objective: To evaluate the e cacy and feasibility of utilizing Traditional Chinese Medicine(TCM) combined group psychotherapy intervention on psychological distress management and gut micro-biome regulation for colorectal(CRC) survivors.Methods: A single-arm phase I clinical trial was conducted between December 2020 and December 2021 in Xiyuan and Beijing Cancer Hospital in China. Inclusion criteria was stage I-III CRC survivors after radical surgery with age between 18-75. The intervention was a six-week online TCM combined group psychotherapy intervention including 90 minutes' communication, TCM lifestyle coaching, self-acupressure guidance and mindfulness practice led by TCM oncologist and psychiatrist each week. Outcomes were measured by Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Fear of Cancer Recurrence Inventor (FCRI), and Quality of Life Questionnaire(QLQ-C30). Fetal samples before and after intervention were collected for 16Sr RNA analysis.Results: We recruited 40 CRC survivors and 38 of them nally completed all interventions with average age of 58±13 years' old. Paired t-test showed that SAS at week 2(35.4±5.8), week 4(37.9±10.5) and week 6(31.3±6.4) during the intervention was signi cantly lower than baseline (42.1±8.3, p<0.05 respectively). SDS score also declined substantially from baseline (38.8±10.7) to week 2(28.3±8.8, p<0.001) and week 6(25.4±7.7, p<0.001). FCRI decreased from 19.4±7.2 at baseline to 17.5±7.1 at week 4(p=0.038) and 16.3±5.8 at week 6(p=0.008). Although changes of QLQ-C30 were not statistically prominent, insomnia and fatigue signi cantly alleviated. The abundances of gut microbiota Intestinibacter, Terrisporobacter, Coprobacter and Gordonibacter were all signi cantly elevated after intervention.Conclusions: TCM combined group psychotherapy intervention is feasible and effective to reduce CRC survivors' psychological distress and modulate certain gut bacteria which might be associated with braingut axis effect. It is necessary to carry out with phase II randomized controlled clinical trial.

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Section: Introductionmentioning

confidence: 99%

Effect of traditional Chinese medicine combined group psychotherapy on psychological distress management and gut micro-biome regulation for colorectal cancer survivors: a single-arm phase I clinical trial

Sun,

Pang,

Wang

et al. 2023

Support Care Cancer

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Effect of Traditional Chinese Medicine Combined Group Psychotherapy on Psychological Distress Management and Gut Micro-biome Regulation for Colorectal Cancer Survivors: A Single-arm Phase I Clinical Trial

Sun

Pang

Wang

et al. 2023

Preprint

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Objective: To evaluate the efficacy and feasibility of utilizing Traditional Chinese Medicine(TCM) combined group psychotherapy intervention on psychological distress management and gut micro-biome regulation for colorectal(CRC) survivors. Methods: A single-arm phase I clinical trial was conducted between December 2020 and December 2021 in Xiyuan and Beijing Cancer Hospital in China. Inclusion criteria was stage I-III CRC survivors after radical surgery with age between 18-75. The intervention was a six-week online TCM combined group psychotherapy intervention including 90 minutes’ communication, TCM lifestyle coaching, self-acupressure guidance and mindfulness practice led by TCM oncologist and psychiatrist each week. Outcomes were measured by Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Fear of Cancer Recurrence Inventor (FCRI), and Quality of Life Questionnaire(QLQ-C30). Fetal samples before and after intervention were collected for 16Sr RNA analysis. Results: We recruited 40 CRC survivors and 38 of them finally completed all interventions with average age of 58±13 years’ old. Paired t-test showed that SAS at week 2(35.4±5.8), week 4(37.9±10.5) and week 6(31.3±6.4) during the intervention was significantly lower than baseline (42.1±8.3, p<0.05 respectively). SDS score also declined substantially from baseline (38.8±10.7) to week 2(28.3±8.8, p<0.001) and week 6(25.4±7.7, p<0.001). FCRI decreased from 19.4±7.2 at baseline to 17.5±7.1 at week 4(p=0.038) and 16.3±5.8 at week 6(p=0.008). Although changes of QLQ-C30 were not statistically prominent, insomnia and fatigue significantly alleviated. The abundances of gut microbiota Intestinibacter, Terrisporobacter, Coprobacter and Gordonibacter were all significantly elevated after intervention. Conclusions: TCM combined group psychotherapy intervention is feasible and effective to reduce CRC survivors’ psychological distress and modulate certain gut bacteria which might be associated with brain-gut axis effect. It is necessary to carry out with phase II randomized controlled clinical trial.

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Effect of meditation, muscle relaxation exercises, dietary and lifestyle modification on depression, anxiety, stress and self-esteem among women undergoing infertility treatment: A randomized controlled trial: Pilot protocol

Aulakh,

Uppal,

Pahwa

2024

Journal of Education and Health Promotion

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BACKGROUND: Infertility is not only a reproductive health problem; it’s also emotionally painful. Currently, treatments for infertility are receiving more attention, but emotional support is equally important. The aim of this study was to assess the effect of meditation, exercises, dietary, and life-style modifications on depression, anxiety, stress, and self-esteem among infertile women. MATERIAL AND METHODS: This randomized controlled trial was carried out on randomly assigned 60 infertile women (30 experimental and 30 control groups) with the above-mentioned distress at the Infertility Clinic of a tertiary-level hospital in India during the period from 01.07.2020 to 30.6.2021. Infertile women were enrolled using a systematic random sampling technique. The pretest was done with the Depression, Anxiety and Stress Scale (DASS) and the Rosenberg self-esteem scale. Interventions were operated on an experimental group for five subsequent visits for 60 minutes and the control group received routine care. A post-test was done on sixth visit. RESULTS: The pretest mean score of infertile women was 16.13 ± 4.95 for depression, 18.93 ± 4.26 for anxiety, 29.27 ± 4.59 for stress and 10.47 ± 3.49 for self-esteem, respectively. The post-test mean score was 9.07 ± 3.14 for depression, 10.73 ± 3.17 for anxiety, 18.4 ± 3.77 for stress, and 17.5 ± 1.96 for self-esteem. The study results showed the post-test mean score was significantly different in the experimental and control groups at P < 0.001. CONCLUSION: These complementary therapies could potentially lessen the emotional distress experienced by infertile women and boost pregnancy rates. So, infertility management should be comprehensive instead of only using medical treatment to get a better outcome.

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The use of integrative medical services to address psychological concerns around infertility in an Indian academic medical centre

Cited by 3 publications

References 29 publications

Effect of traditional Chinese medicine combined group psychotherapy on psychological distress management and gut micro-biome regulation for colorectal cancer survivors: a single-arm phase I clinical trial

Effect of traditional Chinese medicine combined group psychotherapy on psychological distress management and gut micro-biome regulation for colorectal cancer survivors: a single-arm phase I clinical trial

Effect of Traditional Chinese Medicine Combined Group Psychotherapy on Psychological Distress Management and Gut Micro-biome Regulation for Colorectal Cancer Survivors: A Single-arm Phase I Clinical Trial

Effect of meditation, muscle relaxation exercises, dietary and lifestyle modification on depression, anxiety, stress and self-esteem among women undergoing infertility treatment: A randomized controlled trial: Pilot protocol

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