2016
DOI: 10.1053/j.jvca.2015.03.025
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The Use of Intraoperative Dexmedetomidine Is Not Associated With a Reduction in Acute Kidney Injury After Lung Cancer Surgery

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Cited by 21 publications
(28 citation statements)
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“…The primary outcome of this study was AKI incidence within 72 h after surgery, on postoperative day 7 and the time of hospital discharge. We estimated the incidence of AKI using AKIN criteria as defined in previous studies [14,15].…”
Section: Discussionmentioning
confidence: 99%
“…The primary outcome of this study was AKI incidence within 72 h after surgery, on postoperative day 7 and the time of hospital discharge. We estimated the incidence of AKI using AKIN criteria as defined in previous studies [14,15].…”
Section: Discussionmentioning
confidence: 99%
“…A total of 19 studies with 3,395 patients were included in the final pooled analyses. [3][4][5][6][7][8][11][12][13][14][15][16][17][18][19][20][21][22][23] Of these patients, 1,683 received dexmedetomidine while 1,652 did not. Study review and inclusion is outlined in Figure 1.…”
Section: Manuscript Identification and Characteristicsmentioning
confidence: 99%
“…In a placebo-controlled double-blind RCT dexmedetomidine demonstrated significant diuretic effects, with an almost 75% increase in diuresis after cardiac surgery, but did not affect renal function per se [180]. Observational trials indicated protection of kidney function after cardiac surgery [181] but not when used for sedation during lung cancer resection [182]. A placebo-controlled study in 90 patients undergoing coronary artery bypass graft (CABG) showed a dose-dependent reduction of NGAL levels with dexmedetomidine used for postoperative sedation [183].…”
Section: Sedationmentioning
confidence: 99%