The use of mannitol in partial and live donor nephrectomy: an international survey

Abstract

A large majority of high-volume centers performing PN and LDN use mannitol for renoprotection. Since there are no data proving its value nor standardized indication and usage, this survey may provide information for a randomized prospective study.

Laparoscopic retroperitoneal partial nephrectomy using an ergonomic chair: demonstration of technique and matched‐pair analysis

“…There is consensus in the literature that WIT should be restricted to <20 min, which we were able to do in most of our cases . These results have been based on studies with solitary kidneys .…”

“…At this point, 12.5 g mannitol is administered i.v. . After clamping of the renal artery using a bulldog clamp, excision of the tumour is carried out, trying to preserve a 5‐mm rim of normal renal tissue around the tumour according to the principles of enucleo‐resection .…”

“…Despite the shorter WIT, postoperative renal function did not differ between the groups. The impact of ETHOS on surgeons' physical ergonomics has been studied extensively previously, showing a significant reduction of the mean complaint score from 31.6 (20-40) to 13.9 (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24), mainly as a result of less shoulder stiffness, arm pain, hand pain, wrist stiffness, back and leg pain [12,13].…”

“…The use of an ergonomic platform (ETHOS chair) has played an important role in this, independently of the plateau in the learning curve. The ergonomic advantages for the surgeon have been published previously [14,36]. Similarly to the Da Vinci-robot console, the armrest improves the suturing technique, but with the added advantage for the surgeon of a significant reduction of fatigue whilst bedside (Fig.…”

Editorial for a special issue on kidney transplant

“…Specifically, mannitol has been matter of interest due to its presumed antioxidant activity, reduction in the alteration of microcirculatory compliance and increase in the perfusion pressure. Despite the lack of evidence, a recent report by Cosentino et al [6] has surveyed the use of diuretics in high volume centers. Result revealed the preference to use mannitol as a kidney protector; however, the timing of administration and dosage appeared to be operator dependant.…”