ObjectiveTo search, evaluate and summarize the best evidence on nurse burnout intervention at home and abroad, and provide evidence-based basis for clinical nursing staff.MethodsThe literature on nurse burnout intervention was searched in Chinese and English guideline websites and databases, including guidelines, evidence summaries, systematic reviews, clinical decision-making, expert consensus, and randomized controlled studies. The search period was from database establishment to December 31, 2023.Results16 articles were included, including 1 guideline, 1 consensus, 1 evidence summary, 1 randomized controlled study, and 12 systematic reviews. After comprehensive analysis and induction, we extracted five aspects, including effective communication, self-care, resource support, education and training, and social environment, with a total of 15 best evidence.ConclusionThe best evidence for evidence-based intervention for nurse burnout is scientific and practical, and can provide a certain reference for clinical practice in reducing nurse burnout.