The use of Nanocarriers for Drug Delivery in Cancer Therapy David R. Khan

Khan, David R.

doi:10.4172/1948-5956.1000024

Cited by 66 publications

(33 citation statements)

References 52 publications

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“…Liposomes and micelles seems promising with drug transfer to tumor cells within the tumor site. Immunomicelles containing a photosensitizing agent and tumor-specific monoclonal antibody have been successfully used in photodynamic therapy against murine lewis lung carcinoma [36].…”

Section: Relevant Curing Methodologiesmentioning

confidence: 99%

Vaccine Potentiality and Stem Cells Enhancing Cure to Cancer

Parthasarathi¹,

Palki²

2011

J Cancer Sci Ther

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Vaccine potentiality and stem cell therapy is the new development in curing the Cancer. There are different types of cancer and different curing methods are being discussed by different scientist. The new diagnostic methods using DNA vaccine, adjuvants and target oriented cells methods are used in a descriptive method. The stem cell therapy also enhancing in identifying the site of tumour regenesis and curing the tumour by inducing different target oriented cells like chemokines and interleukin (IL). Beside these mesenchymal stem cells also regenerates the new cell lines for new target oriented cells. Hence no doubt at molecular level, the alteration of stem cell self-renewal pathways has been recognized as an essential step for cancer stem cells transformation. Influencive study and therapy will help to eradicate the disease and vaccines or stem cells will be new era in pharmaceuticals for Cancer.

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Section: Relevant Curing Methodologiesmentioning

confidence: 99%

Vaccine Potentiality and Stem Cells Enhancing Cure to Cancer

Parthasarathi¹,

Palki²

2011

J Cancer Sci Ther

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“…There are limitations in drug efficacy as these preparations are full of some cytotoxic agents commonly. For example, DOX, releases from its nanocarrier as there is high empathy or kinship between the drug and a variety of extracellular elements, as a result it has constrained cancer tissue permeability [18]. An innovative delivery podium that ensures the direct cytosolic release of a mammoth miscellany of therapeutics, for example protein, chemotherapy drugs and small interfering RNAs, is known as nanoparticle-stabilized capsule (NPSC) [19].…”

Section: A Rt I C L E I N F O Abstractmentioning

confidence: 99%

Liposome as nanocarrier: Site targeted delivery in lung cancer

Ullah¹,

Noreen²,

Tehreem³

et al. 2017

APJTD

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“…Although the conventional methods for treating the cancer cells are many, some if not all are coupled with a side effect that in the long run proves lethal to the patient [11]. Radiotherapy for cancer cells proved to be an effective way of eliminating cancer cells by targeting the tumour cells through radiation blast without focussing on the adjacent normal cells.…”

Section: Edge Over Conventional Therapiesmentioning

confidence: 99%

Autologous Gene Therapy - A Proactive Approach to Cancer Critique

Ahmad¹

2014

J Cancer Sci Ther

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Gene therapy has a vast range of applications not only restricted to AbstractCancer is one of the most prevalent diseases that affect the major population with each year the frequency is increasing exponentially. Patients with diagnosed cancer are generally treated with the conventional therapies like radiation therapy, chemotherapy. However the survival rate and the life span are known to prolonged, these therapies are quite problematic let alone their detrimental side effects. Gene therapy on the other hand is quite promising since the body's immune response is not compromised while targeting the cancerous cell. While getting further insights into the complex pathways and mechanisms associated with the development of malignant cells has led to the identification more sophisticated and specified cancer therapies, it nevertheless remains imperative to execute the conventional therapies and the associated anticancer drug molecules. Various characteristic features like less toxicity and ability to induce an immune response make the therapy quite probable for various cancers like pancreatic, ovarian and Glioblastoma. Based on the results obtained from pre-clinical studies in model animals, it has set stage for the commercialization of the human trials. The advantages associated with this therapy for the treatment has started attracting focus to further modify and optimize the procedures for better results.

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The use of Nanocarriers for Drug Delivery in Cancer Therapy David R. Khan

Cited by 66 publications

References 52 publications

Vaccine Potentiality and Stem Cells Enhancing Cure to Cancer

Vaccine Potentiality and Stem Cells Enhancing Cure to Cancer

Liposome as nanocarrier: Site targeted delivery in lung cancer

Autologous Gene Therapy - A Proactive Approach to Cancer Critique

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