The use of nifedipine during the postpartum period in patients with severe preeclampsia

A randomized trial of intravenous labetalol and oral nifedipine in severe pregnancy induced hypertension

“…From previous study it was attributed that, nifedipine can enhance urine output after selective renal arteriolar vasodilatation & which was reported in randomized controlled trials involving postpartum pre-eclamptic patients. 8 In our study it was again proved that, patients treated with nifedipine had experienced a significant increase in urine output in comparison to labetalol treated patients. One hour after initial dosing, patients receiving nifedipine showed significant urine output volume than those of patients receiving labetalol.…”

“…Even previously used hydralazine as a standard agent in severe PIH, had lost its popularity, because of its propensity to increase myocardial oxygen demand. Nifedipine has now been used safely in a number of obstetrical trials for the treatment of hypertensive emergencies 1,8,10,11 & as a tocolytic agent in several randomized clinical trials. 1,2 In this study, the patients achieved the goal blood pressure after 2 to 3 doses of nifedipine & because of this; the smaller concentration of nifedipine was …”

Short-term treatment of severe hypertension of pregnancy: prospective comparison of nicardipine and labetalol

“…Nifedipine proved to be safe and efficient in pregnancy induced hypertension [18,20,21,22,23]. However, oral nifedipine lowers BP within 20-30 min, with an effect that is not controllable and which lasts up to 3-4 h or even longer [24].…”

Anestesia na Pré-Eclâmpsia

“…Existe a possibilidade de ocorrer hipotensão arterial grave com subseqüente sofrimento fetal agudo em pacientes que estão recebendo sulfato de magnésio 9 . O magnésio também atua como bloqueador de canal de cálcio 55 . A nitroglicerina, potente venodilatador, apresenta rápido iní-cio de ação e curta duração de ação.…”

“…There is the possibility of severe arterial hypotension with subsequent acute fetal suffering in patients receiving magnesium sulphate 9 . Magnesium is also a calcium channel blocker 55 . Nitroglycerine, a potent vasodilator, has a fast onset and short duration.…”