The Use of Pancreatoscopy in the Diagnosis of Intraductal Papillary Mucinous Tumor Lesions of the Pancreas

Zalecenia ogólne dotyczące postępowania w nowotworach neuroendokrynnych układu pokarmowego (rekomendowane przez Polską Sieć Guzów Neuroendokrynnych)

“…It allows better, compared to EUS, visualisation of pancreatic NEN in the immediate vicinity of the pancreatic duct, and of the endo-luminal lesions. Sensitivity of this examination is approximately 94% [56], and it increases to almost 100% for the lesions larger than 3 mm, located in the pancreatic duct [57].…”

EUS in Pancreatic Cysts

“…15). Characteristic findings include papillary tumor and fish-egg-like appearance in 73 % [68]. Irrigation cytology (aspiration of saline irrigated into the duct during pancreatoscopy) may diagnose malignancy better than targeted biopsies during pancreatoscopy (100 % sensitive and specific versus 25 % sensitive) [69].…”

“…Mild complications of cholangitis and pancreatitis occurred in 24 %. Small Japanese case series of resected IPMN suggest preoperative pancreatoscopy and IDUS are valuable for evaluating the extent of ductal involvement to aid the surgeons in mapping their resection [68,70,71]. Which part and how much of the pancreas to resect are important in MD-IPMN because total pancreatectomy may be morbid with brittle diabetes and exocrine insufficiency, and partial resection with the goal of negative margins may be more suitable for older patients with comorbidities.…”

Diagnostic and Therapeutic Procedures in Gastroenterology

“…Pancreatic juice collected during pancreatoscopy has been shown to provide a better yield for cytologic evaluation than traditional catheter collection (Uehara et al 1997). Many other studies have shown the improved diagnostic benefits of pancreatoscopy, especially in regard to evaluating IPMNs (Kaneko et al 1998;Kozarek 1988b;Fujita et al 1990;Hara et al 2002;Yamao et al 2003;Kodama et al 2002;Mukai et al 1998;Yasuda et al 2005). Recently, peroral pancreatoscopy has been combined with narrow-band imaging to emphasize certain image features often seen with IPMNs, such as mucosal structures and capillary vessels (Itoi et al 2007).…”